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A comparative study of the laboratory features of COVID‐19 and other viral pneumonias in the recovery stage

BACKGROUND: Clinical recovery does not mean full recovery. It is necessary to explore the aftereffects of COVID‐19 in patients and compare the laboratory features of COVID‐19 and other viral pneumonias in the recovery stages. METHODS: Forty‐seven cases of COVID‐19 and 45 cases of other viral pneumon...

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Autores principales: Zhao, Guolian, Su, Yingying, Sun, Xiaomeng, Cui, Xiaoli, Dang, Liyun, Zhao, Lijuan, Tan, Xiaowen, Wang, Hongrui, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404602/
https://www.ncbi.nlm.nih.gov/pubmed/32696465
http://dx.doi.org/10.1002/jcla.23483
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author Zhao, Guolian
Su, Yingying
Sun, Xiaomeng
Cui, Xiaoli
Dang, Liyun
Zhao, Lijuan
Tan, Xiaowen
Wang, Hongrui
Yang, Ming
author_facet Zhao, Guolian
Su, Yingying
Sun, Xiaomeng
Cui, Xiaoli
Dang, Liyun
Zhao, Lijuan
Tan, Xiaowen
Wang, Hongrui
Yang, Ming
author_sort Zhao, Guolian
collection PubMed
description BACKGROUND: Clinical recovery does not mean full recovery. It is necessary to explore the aftereffects of COVID‐19 in patients and compare the laboratory features of COVID‐19 and other viral pneumonias in the recovery stages. METHODS: Forty‐seven cases of COVID‐19 and 45 cases of other viral pneumonias (control) were included in this study. The laboratory parameters were compared between COVID‐19 and control patients as well as severe and moderate COVID‐19 patients from the clinical recovery stage to the 4 weeks postdischarge recovery stage. RESULTS: A higher RDW‐CV level and neutrophil percentage and lower levels of total proteins, lymphocytes, eosinophils, and MCH were found in COVID‐19 patients compared with those in controls from the clinical recovery to the postdischarge recovery stages. Further analysis showed that decreases in lymphocytes, total proteins, and SOD and elevations in neutrophils, FDP, CRP, and ESR were more common in severe than moderate cases of COVID‐19 during hospitalization; however, differences in these indicators, except total proteins, were not observed in the postdischarge recovery stages. Additionally, only 76.9% of COVID‐19 patients were positive for IgG antibodies against SARS‐CoV‐2 in the convalescence stage, and one patient that was negative for specific IgG was reinfected. CONCLUSIONS: This study demonstrated that patients recovering from COVID‐19 might need better care than that patients with other viral pneumonias due to the possibility of having poor immunity and nutritional conditions. These findings provide new insights to improve the understanding of COVID‐19 and improve care for patients affected by these kinds of pandemics in the future.
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spelling pubmed-74046022020-08-05 A comparative study of the laboratory features of COVID‐19 and other viral pneumonias in the recovery stage Zhao, Guolian Su, Yingying Sun, Xiaomeng Cui, Xiaoli Dang, Liyun Zhao, Lijuan Tan, Xiaowen Wang, Hongrui Yang, Ming J Clin Lab Anal Research Articles BACKGROUND: Clinical recovery does not mean full recovery. It is necessary to explore the aftereffects of COVID‐19 in patients and compare the laboratory features of COVID‐19 and other viral pneumonias in the recovery stages. METHODS: Forty‐seven cases of COVID‐19 and 45 cases of other viral pneumonias (control) were included in this study. The laboratory parameters were compared between COVID‐19 and control patients as well as severe and moderate COVID‐19 patients from the clinical recovery stage to the 4 weeks postdischarge recovery stage. RESULTS: A higher RDW‐CV level and neutrophil percentage and lower levels of total proteins, lymphocytes, eosinophils, and MCH were found in COVID‐19 patients compared with those in controls from the clinical recovery to the postdischarge recovery stages. Further analysis showed that decreases in lymphocytes, total proteins, and SOD and elevations in neutrophils, FDP, CRP, and ESR were more common in severe than moderate cases of COVID‐19 during hospitalization; however, differences in these indicators, except total proteins, were not observed in the postdischarge recovery stages. Additionally, only 76.9% of COVID‐19 patients were positive for IgG antibodies against SARS‐CoV‐2 in the convalescence stage, and one patient that was negative for specific IgG was reinfected. CONCLUSIONS: This study demonstrated that patients recovering from COVID‐19 might need better care than that patients with other viral pneumonias due to the possibility of having poor immunity and nutritional conditions. These findings provide new insights to improve the understanding of COVID‐19 and improve care for patients affected by these kinds of pandemics in the future. John Wiley and Sons Inc. 2020-07-21 /pmc/articles/PMC7404602/ /pubmed/32696465 http://dx.doi.org/10.1002/jcla.23483 Text en © 2020 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Zhao, Guolian
Su, Yingying
Sun, Xiaomeng
Cui, Xiaoli
Dang, Liyun
Zhao, Lijuan
Tan, Xiaowen
Wang, Hongrui
Yang, Ming
A comparative study of the laboratory features of COVID‐19 and other viral pneumonias in the recovery stage
title A comparative study of the laboratory features of COVID‐19 and other viral pneumonias in the recovery stage
title_full A comparative study of the laboratory features of COVID‐19 and other viral pneumonias in the recovery stage
title_fullStr A comparative study of the laboratory features of COVID‐19 and other viral pneumonias in the recovery stage
title_full_unstemmed A comparative study of the laboratory features of COVID‐19 and other viral pneumonias in the recovery stage
title_short A comparative study of the laboratory features of COVID‐19 and other viral pneumonias in the recovery stage
title_sort comparative study of the laboratory features of covid‐19 and other viral pneumonias in the recovery stage
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404602/
https://www.ncbi.nlm.nih.gov/pubmed/32696465
http://dx.doi.org/10.1002/jcla.23483
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