Cargando…

Trimebutine Maleate Monotherapy for Functional Dyspepsia: A Multicenter, Randomized, Double-Blind Placebo Controlled Prospective Trial

Background and Objectives: Functional dyspepsia (FD) is one of the most common functional gastrointestinal disorders; it has a great impact on patient quality of life and is difficult to treat satisfactorily. This study evaluates the efficacy and safety of trimebutine maleate (TM) in patients with F...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kountouras, Jannis, Gavalas, Emmanuel, Papaefthymiou, Apostolis, Tsechelidis, Ioannis, Polyzos, Stergios A., Bor, Serhat, Diculescu, Mircea, Jadallah, Κhaled, Tadeusz, Mazurek, Karakan, Tarkan, Bochenek, Anna, Rozciecha, Jerzy, Dabrowski, Piotr, Sparchez, Zeno, Sezgin, Orhan, Gülten, Macit, Farsakh, Niazy Abu, Doulberis, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404657/ https://www.ncbi.nlm.nih.gov/pubmed/32650518 http://dx.doi.org/10.3390/medicina56070339

Ejemplares similares

The Effect of Trimebutine and/or Helicobacter pylori Eradication on the Gastroesophageal Reflux Disease, Irritable Bowel Syndrome, and Functional Dyspepsia Overlapping Disorders
por: Kountouras, Jannis, et al.
Publicado: (2019)

Gastroesophageal reflux disease, irritable bowel syndrome and functional dyspepsia as overlapping conditions: focus on effect of trimebutine
por: Kountouras, Jannis, et al.
Publicado: (2019)

National consensus on Helicobacter pylori infection: the next-day challenge
por: Papaefthymiou, Apostolis, et al.
Publicado: (2020)

Special Issue “Extragastric Disorders of Helicobacter pylori Infection: From Diagnosis to Treatment”: Editorial
por: Doulberis, Michael, et al.
Publicado: (2023)

Diagnostic approach to Helicobacter pylori-related gastric oncogenesis
por: Rupp, Sebastian, et al.
Publicado: (2022)

The Potential Role of Super Spread Events in SARS-COV-2 Pandemic; a Narrative Review
por: Kyriakopoulos, Anthony M., et al.
Publicado: (2020)

COVID-19 mRNA Vaccine Effectiveness against Elderly Frail People
por: Kountouras, Jannis, et al.
Publicado: (2023)

Role of autophagy in gastric carcinogenesis
por: Papaefthymiou, Apostolis, et al.
Publicado: (2021)

Association between Active Helicobacter pylori Infection and Glaucoma: A Systematic Review and Meta-Analysis
por: Doulberis, Michael, et al.
Publicado: (2020)

Active Helicobacter pylori Infection is Independently Associated with Nonalcoholic Steatohepatitis in Morbidly Obese Patients
por: Doulberis, Michael, et al.
Publicado: (2020)

Impact of Helicobacter pylori-related Microbial Dysbiosis in the Pathogenesis of Metabolic Syndrome and Gastrointestinal Dysmotility Disorders
por: Kountouras, Jannis, et al.
Publicado: (2021)

Repositioning Trimebutine Maleate as a Cancer Treatment Targeting Ovarian Cancer Stem Cells
por: Lee, Heejin, et al.
Publicado: (2021)

Impact of Helicobacter pylori-related Metabolic Syndrome and Gastroesophageal Reflux Disease on the Risk of Acute Myocardial Infarction
por: Kountouras, Jannis, et al.
Publicado: (2021)

Impact of Helicobacter pylori-Related Metabolic Syndrome Parameters on Arterial Hypertension
por: Kountouras, Jannis, et al.
Publicado: (2021)

Vitamin D Deficiency and Unclear Abdominal Pain in Patients from Low- and Middle-Income Countries
por: Doulberis, Michael, et al.
Publicado: (2019)

Controlling the Impact of Helicobacter pylori-Related Hyperhomocysteinemia on Neurodegeneration
por: Kountouras, Jannis, et al.
Publicado: (2023)

Impacto da Síndrome Metabólica Relacionada à Infecção por Helicobacter pylori Ativa na Hipertensão Arterial Sistêmica
por: Kountouras, Jannis, et al.
Publicado: (2022)

The protective impact of adapted trimebutine maleate-loaded nanostructured lipid carriers for alleviating the severity of acute colitis
por: Motawea, Amira, et al.
Publicado: (2022)

Efficacy and Mechanism of Trimebutine Maleate Combined with Lactulose in the Treatment of Constipation-Predominant Irritable Bowel Syndrome in the Elderly
por: Zhou, Yeping, et al.
Publicado: (2022)

The impact of COVID-19 pandemic on gastrointestinal diseases: a single-center cross-sectional study in central Greece
por: Papaefthymiou, Apostolis, et al.
Publicado: (2021)

Should the economic pillar be included in national, European or global consensuses concerning Helicobacter pylori infection treatments?
por: Liatsos, Christos, et al.
Publicado: (2020)

Metabolic syndrome components including high abdominal obesity and sarcopenia in patients with inflammatory bowel disease
por: Kountouras, Jannis, et al.
Publicado: (2019)

Helicobacter pylori-Related Metabolic Parameters and Premalignant Gastric Mucosa Histological Lesions in Swiss Bariatric Patients
por: Doulberis, Michael, et al.
Publicado: (2021)

The impact of selective serotonin receptor inhibitors on post-endoscopic sphincterotomy bleeding, alone or with concurrent aspirin or nonsteroidal anti-inflammatory drugs
por: Katsinelos, Panagiotis, et al.
Publicado: (2019)

Helicobacter pylori, gastric microbiota and gastric cancer relationship: Unrolling the tangle
por: Liatsos, Christos, et al.
Publicado: (2022)

Innate immunity and nonalcoholic fatty liver disease
por: Kountouras, Jannis, et al.
Publicado: (2023)

Autonomic Dysfunction and Somatization in Young Patients With Irritable Bowel Syndrome and Mitral Valve Prolapse Syndrome
por: Kountouras, Jannis, et al.
Publicado: (2023)

Association between Helicobacter pylori Infection and Nasal Polyps: A Systematic Review and Meta-Analysis
por: Doulberis, Michael, et al.
Publicado: (2023)

Ofeleein i mi Vlaptin—Volume II: Immunity Following Infection or mRNA Vaccination, Drug Therapies and Non-Pharmacological Management at Post-Two Years SARS-CoV-2 Pandemic
por: Kountouras, Jannis, et al.
Publicado: (2022)

Efficacy of probiotics and trimebutine maleate for abemaciclib-induced diarrhea: A randomized, open-label phase II trial (MERMAID, WJOG11318B)
por: Masuda, Hiroko, et al.
Publicado: (2023)

Helicobacter pylori infection and esophageal adenocarcinoma: a review and a personal view
por: Polyzos, Stergios A., et al.
Publicado: (2018)

Evaluation of the Direct Economic Cost per Eradication Treatment Regimen against Helicobacter pylori Infection in Greece: Do National Health Policy-Makers Need to Care?
por: Liatsos, Christos, et al.
Publicado: (2020)

The Effect of Trimebutine on the Overlap Syndrome Model of Guinea Pigs
por: Hussain, Zahid, et al.
Publicado: (2018)

Viral Hepatitis and Hepatocellular Carcinoma: State of the Art
por: Datfar, Toofan, et al.
Publicado: (2021)

Active Helicobacter pylori Infection Is a Risk Factor for Colorectal Mucosa: Early and Advanced Colonic Neoplasm Sequence
por: Kountouras, Jannis, et al.
Publicado: (2017)

Relationship between Helicobacter pylori infection and multiple sclerosis
por: Gavalas, Emmanuel, et al.
Publicado: (2015)

Mortality in Cyprus Over the Period 2016-2021
por: Avraam, Demetris, et al.
Publicado: (2022)

Trimebutine Promotes Glioma Cell Apoptosis as a Potential Anti-tumor Agent
por: Fan, Yi-pu, et al.
Publicado: (2018)

The potentially dual-faceted nature of fetuin-A in Helicobacter pylori infection and insulin resistance
por: Polyzos, Stergios A., et al.
Publicado: (2011)

Comment on: Jeon et al. Helicobacter pylori Infection Is Associated With an Increased Rate of Diabetes. Diabetes Care 2012;35:520–525
por: Polyzos, Stergios A., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_0asm7en89q63tqeigdjcrgle8t