Cargando…

Opportunities for biomaterials to address the challenges of COVID‐19

The coronavirus disease 2019 (COVID‐19) pandemic has revealed major shortcomings in our ability to mitigate transmission of infectious viral disease and provide treatment to patients, resulting in a public health crisis. Within months of the first reported case in China, the virus has spread worldwi...

Descripción completa

Detalles Bibliográficos
Autores principales: Chakhalian, Daniel, Shultz, Robert B., Miles, Catherine E., Kohn, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405498/
https://www.ncbi.nlm.nih.gov/pubmed/32662571
http://dx.doi.org/10.1002/jbm.a.37059
_version_ 1783567257493831680
author Chakhalian, Daniel
Shultz, Robert B.
Miles, Catherine E.
Kohn, Joachim
author_facet Chakhalian, Daniel
Shultz, Robert B.
Miles, Catherine E.
Kohn, Joachim
author_sort Chakhalian, Daniel
collection PubMed
description The coronavirus disease 2019 (COVID‐19) pandemic has revealed major shortcomings in our ability to mitigate transmission of infectious viral disease and provide treatment to patients, resulting in a public health crisis. Within months of the first reported case in China, the virus has spread worldwide at an unprecedented rate. COVID‐19 illustrates that the biomaterials community was engaged in significant research efforts against bacteria and fungi with relatively little effort devoted to viruses. Accordingly, biomaterials scientists and engineers will have to participate in multidisciplinary antiviral research over the coming years. Although tissue engineering and regenerative medicine have historically dominated the field of biomaterials, current research holds promise for providing transformative solutions to viral outbreaks. To facilitate collaboration, it is imperative to establish a mutual language and adequate understanding between clinicians, industry partners, and research scientists. In this article, clinical perspectives are shared to clearly define emerging healthcare needs that can be met by biomaterials solutions. Strategies and opportunities for novel biomaterials intervention spanning diagnostics, treatment strategies, vaccines, and virus‐deactivating surface coatings are discussed. Ultimately this review serves as a call for the biomaterials community to become a leading contributor to the prevention and management of the current and future viral outbreaks.
format Online
Article
Text
id pubmed-7405498
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley & Sons, Inc.
record_format MEDLINE/PubMed
spelling pubmed-74054982020-08-05 Opportunities for biomaterials to address the challenges of COVID‐19 Chakhalian, Daniel Shultz, Robert B. Miles, Catherine E. Kohn, Joachim J Biomed Mater Res A Review Article The coronavirus disease 2019 (COVID‐19) pandemic has revealed major shortcomings in our ability to mitigate transmission of infectious viral disease and provide treatment to patients, resulting in a public health crisis. Within months of the first reported case in China, the virus has spread worldwide at an unprecedented rate. COVID‐19 illustrates that the biomaterials community was engaged in significant research efforts against bacteria and fungi with relatively little effort devoted to viruses. Accordingly, biomaterials scientists and engineers will have to participate in multidisciplinary antiviral research over the coming years. Although tissue engineering and regenerative medicine have historically dominated the field of biomaterials, current research holds promise for providing transformative solutions to viral outbreaks. To facilitate collaboration, it is imperative to establish a mutual language and adequate understanding between clinicians, industry partners, and research scientists. In this article, clinical perspectives are shared to clearly define emerging healthcare needs that can be met by biomaterials solutions. Strategies and opportunities for novel biomaterials intervention spanning diagnostics, treatment strategies, vaccines, and virus‐deactivating surface coatings are discussed. Ultimately this review serves as a call for the biomaterials community to become a leading contributor to the prevention and management of the current and future viral outbreaks. John Wiley & Sons, Inc. 2020-08-04 2020-10 /pmc/articles/PMC7405498/ /pubmed/32662571 http://dx.doi.org/10.1002/jbm.a.37059 Text en © 2020 The Authors. Journal of Biomedical Materials Research Part A published by Wiley Periodicals LLC https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Review Article
Chakhalian, Daniel
Shultz, Robert B.
Miles, Catherine E.
Kohn, Joachim
Opportunities for biomaterials to address the challenges of COVID‐19
title Opportunities for biomaterials to address the challenges of COVID‐19
title_full Opportunities for biomaterials to address the challenges of COVID‐19
title_fullStr Opportunities for biomaterials to address the challenges of COVID‐19
title_full_unstemmed Opportunities for biomaterials to address the challenges of COVID‐19
title_short Opportunities for biomaterials to address the challenges of COVID‐19
title_sort opportunities for biomaterials to address the challenges of covid‐19
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405498/
https://www.ncbi.nlm.nih.gov/pubmed/32662571
http://dx.doi.org/10.1002/jbm.a.37059
work_keys_str_mv AT chakhaliandaniel opportunitiesforbiomaterialstoaddressthechallengesofcovid19
AT shultzrobertb opportunitiesforbiomaterialstoaddressthechallengesofcovid19
AT milescatherinee opportunitiesforbiomaterialstoaddressthechallengesofcovid19
AT kohnjoachim opportunitiesforbiomaterialstoaddressthechallengesofcovid19