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Opportunities for biomaterials to address the challenges of COVID‐19
The coronavirus disease 2019 (COVID‐19) pandemic has revealed major shortcomings in our ability to mitigate transmission of infectious viral disease and provide treatment to patients, resulting in a public health crisis. Within months of the first reported case in China, the virus has spread worldwi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405498/ https://www.ncbi.nlm.nih.gov/pubmed/32662571 http://dx.doi.org/10.1002/jbm.a.37059 |
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author | Chakhalian, Daniel Shultz, Robert B. Miles, Catherine E. Kohn, Joachim |
author_facet | Chakhalian, Daniel Shultz, Robert B. Miles, Catherine E. Kohn, Joachim |
author_sort | Chakhalian, Daniel |
collection | PubMed |
description | The coronavirus disease 2019 (COVID‐19) pandemic has revealed major shortcomings in our ability to mitigate transmission of infectious viral disease and provide treatment to patients, resulting in a public health crisis. Within months of the first reported case in China, the virus has spread worldwide at an unprecedented rate. COVID‐19 illustrates that the biomaterials community was engaged in significant research efforts against bacteria and fungi with relatively little effort devoted to viruses. Accordingly, biomaterials scientists and engineers will have to participate in multidisciplinary antiviral research over the coming years. Although tissue engineering and regenerative medicine have historically dominated the field of biomaterials, current research holds promise for providing transformative solutions to viral outbreaks. To facilitate collaboration, it is imperative to establish a mutual language and adequate understanding between clinicians, industry partners, and research scientists. In this article, clinical perspectives are shared to clearly define emerging healthcare needs that can be met by biomaterials solutions. Strategies and opportunities for novel biomaterials intervention spanning diagnostics, treatment strategies, vaccines, and virus‐deactivating surface coatings are discussed. Ultimately this review serves as a call for the biomaterials community to become a leading contributor to the prevention and management of the current and future viral outbreaks. |
format | Online Article Text |
id | pubmed-7405498 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74054982020-08-05 Opportunities for biomaterials to address the challenges of COVID‐19 Chakhalian, Daniel Shultz, Robert B. Miles, Catherine E. Kohn, Joachim J Biomed Mater Res A Review Article The coronavirus disease 2019 (COVID‐19) pandemic has revealed major shortcomings in our ability to mitigate transmission of infectious viral disease and provide treatment to patients, resulting in a public health crisis. Within months of the first reported case in China, the virus has spread worldwide at an unprecedented rate. COVID‐19 illustrates that the biomaterials community was engaged in significant research efforts against bacteria and fungi with relatively little effort devoted to viruses. Accordingly, biomaterials scientists and engineers will have to participate in multidisciplinary antiviral research over the coming years. Although tissue engineering and regenerative medicine have historically dominated the field of biomaterials, current research holds promise for providing transformative solutions to viral outbreaks. To facilitate collaboration, it is imperative to establish a mutual language and adequate understanding between clinicians, industry partners, and research scientists. In this article, clinical perspectives are shared to clearly define emerging healthcare needs that can be met by biomaterials solutions. Strategies and opportunities for novel biomaterials intervention spanning diagnostics, treatment strategies, vaccines, and virus‐deactivating surface coatings are discussed. Ultimately this review serves as a call for the biomaterials community to become a leading contributor to the prevention and management of the current and future viral outbreaks. John Wiley & Sons, Inc. 2020-08-04 2020-10 /pmc/articles/PMC7405498/ /pubmed/32662571 http://dx.doi.org/10.1002/jbm.a.37059 Text en © 2020 The Authors. Journal of Biomedical Materials Research Part A published by Wiley Periodicals LLC https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Review Article Chakhalian, Daniel Shultz, Robert B. Miles, Catherine E. Kohn, Joachim Opportunities for biomaterials to address the challenges of COVID‐19 |
title | Opportunities for biomaterials to address the challenges of COVID‐19 |
title_full | Opportunities for biomaterials to address the challenges of COVID‐19 |
title_fullStr | Opportunities for biomaterials to address the challenges of COVID‐19 |
title_full_unstemmed | Opportunities for biomaterials to address the challenges of COVID‐19 |
title_short | Opportunities for biomaterials to address the challenges of COVID‐19 |
title_sort | opportunities for biomaterials to address the challenges of covid‐19 |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405498/ https://www.ncbi.nlm.nih.gov/pubmed/32662571 http://dx.doi.org/10.1002/jbm.a.37059 |
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