Time to clearance of abdominal septic focus and mortality in patients with sepsis

OBJECTIVE: To assess the relationship between time to focus clearance and hospital mortality in patients with sepsis and septic shock. METHODS: This was an observational, single-center study with a retrospective analysis of the time to clearance of abdominal septic focus. Patients were classified ac...

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Detalles Bibliográficos
Autores principales: Moraes, Rafael Barberena, Serafini, Thiago Ferreira, Vidart, Josi, Moretti, Miriane Melo Silveira, Haas, Jaqueline Sangiogo, Pagnoncelli, Alan, Azeredo, Marco Aurélio Abreu, Friedman, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Medicina Intensiva Brasileira - AMIB 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405735/
https://www.ncbi.nlm.nih.gov/pubmed/32667437
http://dx.doi.org/10.5935/0103-507X.20200029
Descripción
Sumario:OBJECTIVE: To assess the relationship between time to focus clearance and hospital mortality in patients with sepsis and septic shock. METHODS: This was an observational, single-center study with a retrospective analysis of the time to clearance of abdominal septic focus. Patients were classified according to the time to focus clearance into an early (≤ 12 hours) or delayed (> 12 hours) group. RESULTS: A total of 135 patients were evaluated. There was no association between time to focus clearance and hospital mortality (≤ 12 hours versus > 12 hours): 52.3% versus 52.9%, with p = 0.137. CONCLUSION: There was no difference in hospital mortality among patients with sepsis or septic shock who had an infectious focus evacuated before or after 12 hours after the diagnosis of sepsis.

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