Time to clearance of abdominal septic focus and mortality in patients with sepsis

OBJECTIVE: To assess the relationship between time to focus clearance and hospital mortality in patients with sepsis and septic shock. METHODS: This was an observational, single-center study with a retrospective analysis of the time to clearance of abdominal septic focus. Patients were classified ac...

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Autores principales: Moraes, Rafael Barberena, Serafini, Thiago Ferreira, Vidart, Josi, Moretti, Miriane Melo Silveira, Haas, Jaqueline Sangiogo, Pagnoncelli, Alan, Azeredo, Marco Aurélio Abreu, Friedman, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Medicina Intensiva Brasileira - AMIB 2020
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Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405735/
https://www.ncbi.nlm.nih.gov/pubmed/32667437
http://dx.doi.org/10.5935/0103-507X.20200029
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author Moraes, Rafael Barberena
Serafini, Thiago Ferreira
Vidart, Josi
Moretti, Miriane Melo Silveira
Haas, Jaqueline Sangiogo
Pagnoncelli, Alan
Azeredo, Marco Aurélio Abreu
Friedman, Gilberto
author_facet Moraes, Rafael Barberena
Serafini, Thiago Ferreira
Vidart, Josi
Moretti, Miriane Melo Silveira
Haas, Jaqueline Sangiogo
Pagnoncelli, Alan
Azeredo, Marco Aurélio Abreu
Friedman, Gilberto
author_sort Moraes, Rafael Barberena
collection PubMed
description OBJECTIVE: To assess the relationship between time to focus clearance and hospital mortality in patients with sepsis and septic shock. METHODS: This was an observational, single-center study with a retrospective analysis of the time to clearance of abdominal septic focus. Patients were classified according to the time to focus clearance into an early (≤ 12 hours) or delayed (> 12 hours) group. RESULTS: A total of 135 patients were evaluated. There was no association between time to focus clearance and hospital mortality (≤ 12 hours versus > 12 hours): 52.3% versus 52.9%, with p = 0.137. CONCLUSION: There was no difference in hospital mortality among patients with sepsis or septic shock who had an infectious focus evacuated before or after 12 hours after the diagnosis of sepsis.
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spelling pubmed-74057352020-08-07 Time to clearance of abdominal septic focus and mortality in patients with sepsis Moraes, Rafael Barberena Serafini, Thiago Ferreira Vidart, Josi Moretti, Miriane Melo Silveira Haas, Jaqueline Sangiogo Pagnoncelli, Alan Azeredo, Marco Aurélio Abreu Friedman, Gilberto Rev Bras Ter Intensiva Original Article OBJECTIVE: To assess the relationship between time to focus clearance and hospital mortality in patients with sepsis and septic shock. METHODS: This was an observational, single-center study with a retrospective analysis of the time to clearance of abdominal septic focus. Patients were classified according to the time to focus clearance into an early (≤ 12 hours) or delayed (> 12 hours) group. RESULTS: A total of 135 patients were evaluated. There was no association between time to focus clearance and hospital mortality (≤ 12 hours versus > 12 hours): 52.3% versus 52.9%, with p = 0.137. CONCLUSION: There was no difference in hospital mortality among patients with sepsis or septic shock who had an infectious focus evacuated before or after 12 hours after the diagnosis of sepsis. Associação de Medicina Intensiva Brasileira - AMIB 2020 /pmc/articles/PMC7405735/ /pubmed/32667437 http://dx.doi.org/10.5935/0103-507X.20200029 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Moraes, Rafael Barberena
Serafini, Thiago Ferreira
Vidart, Josi
Moretti, Miriane Melo Silveira
Haas, Jaqueline Sangiogo
Pagnoncelli, Alan
Azeredo, Marco Aurélio Abreu
Friedman, Gilberto
Time to clearance of abdominal septic focus and mortality in patients with sepsis
title Time to clearance of abdominal septic focus and mortality in patients with sepsis
title_full Time to clearance of abdominal septic focus and mortality in patients with sepsis
title_fullStr Time to clearance of abdominal septic focus and mortality in patients with sepsis
title_full_unstemmed Time to clearance of abdominal septic focus and mortality in patients with sepsis
title_short Time to clearance of abdominal septic focus and mortality in patients with sepsis
title_sort time to clearance of abdominal septic focus and mortality in patients with sepsis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405735/
https://www.ncbi.nlm.nih.gov/pubmed/32667437
http://dx.doi.org/10.5935/0103-507X.20200029
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