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Loss of High-Mobility Group Box 1 (HMGB1) Protein in Rods Accelerates Rod Photoreceptor Degeneration After Retinal Detachment
PURPOSE: Retinal detachment (RD) disrupts the nutritional support and oxygen delivery to photoreceptors (PRs), ultimately causing cell death. High-mobility group box 1 (HMGB1) can serve as an extracellular alarmin when released from stressed cells. PRs release HMGB1 after RD. The purpose of this stu...
Autores principales: | Ross, Bing X., Choi, Joanne, Yao, Jingyu, Hager, Heather M., Abcouwer, Steven F., Zacks, David N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405795/ https://www.ncbi.nlm.nih.gov/pubmed/32460314 http://dx.doi.org/10.1167/iovs.61.5.50 |
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