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Loss of High-Mobility Group Box 1 (HMGB1) Protein in Rods Accelerates Rod Photoreceptor Degeneration After Retinal Detachment

PURPOSE: Retinal detachment (RD) disrupts the nutritional support and oxygen delivery to photoreceptors (PRs), ultimately causing cell death. High-mobility group box 1 (HMGB1) can serve as an extracellular alarmin when released from stressed cells. PRs release HMGB1 after RD. The purpose of this stu...

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Detalles Bibliográficos
Autores principales:	Ross, Bing X., Choi, Joanne, Yao, Jingyu, Hager, Heather M., Abcouwer, Steven F., Zacks, David N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2020
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405795/ https://www.ncbi.nlm.nih.gov/pubmed/32460314 http://dx.doi.org/10.1167/iovs.61.5.50

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