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Human Papillomavirus Positive Squamous Cell Carcinoma of the Rectum

Squamous cell carcinoma (SCC) is most commonly seen in the esophagus and anal canal in the gastrointestinal tract. The incidence of SCC of the rectum is infrequent with no clear etiology. There have been limited reported cases of SCC of the rectum caused by human papillomavirus (HPV). Due to the rar...

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Autores principales: Makadia, Shraddhadevi, Patel, Ishan, Abusaada, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405967/
https://www.ncbi.nlm.nih.gov/pubmed/32775102
http://dx.doi.org/10.7759/cureus.9022
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author Makadia, Shraddhadevi
Patel, Ishan
Abusaada, Khalid
author_facet Makadia, Shraddhadevi
Patel, Ishan
Abusaada, Khalid
author_sort Makadia, Shraddhadevi
collection PubMed
description Squamous cell carcinoma (SCC) is most commonly seen in the esophagus and anal canal in the gastrointestinal tract. The incidence of SCC of the rectum is infrequent with no clear etiology. There have been limited reported cases of SCC of the rectum caused by human papillomavirus (HPV). Due to the rarity of carcinoma, the management of SCC of the rectum is not standardized. We report a case of a 51-year-old female with an insignificant medical history presenting with hematochezia and weight loss and was found to have HPV-positive SCC of the rectum. This case report emphasizes the importance of work-up, usefulness of HPV testing for high-risk patients, and clinical management of SCC of the rectum.
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spelling pubmed-74059672020-08-06 Human Papillomavirus Positive Squamous Cell Carcinoma of the Rectum Makadia, Shraddhadevi Patel, Ishan Abusaada, Khalid Cureus Internal Medicine Squamous cell carcinoma (SCC) is most commonly seen in the esophagus and anal canal in the gastrointestinal tract. The incidence of SCC of the rectum is infrequent with no clear etiology. There have been limited reported cases of SCC of the rectum caused by human papillomavirus (HPV). Due to the rarity of carcinoma, the management of SCC of the rectum is not standardized. We report a case of a 51-year-old female with an insignificant medical history presenting with hematochezia and weight loss and was found to have HPV-positive SCC of the rectum. This case report emphasizes the importance of work-up, usefulness of HPV testing for high-risk patients, and clinical management of SCC of the rectum. Cureus 2020-07-06 /pmc/articles/PMC7405967/ /pubmed/32775102 http://dx.doi.org/10.7759/cureus.9022 Text en Copyright © 2020, Makadia et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Makadia, Shraddhadevi
Patel, Ishan
Abusaada, Khalid
Human Papillomavirus Positive Squamous Cell Carcinoma of the Rectum
title Human Papillomavirus Positive Squamous Cell Carcinoma of the Rectum
title_full Human Papillomavirus Positive Squamous Cell Carcinoma of the Rectum
title_fullStr Human Papillomavirus Positive Squamous Cell Carcinoma of the Rectum
title_full_unstemmed Human Papillomavirus Positive Squamous Cell Carcinoma of the Rectum
title_short Human Papillomavirus Positive Squamous Cell Carcinoma of the Rectum
title_sort human papillomavirus positive squamous cell carcinoma of the rectum
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405967/
https://www.ncbi.nlm.nih.gov/pubmed/32775102
http://dx.doi.org/10.7759/cureus.9022
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