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Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear?
Gastro-oesophageal reflux disease, eosinophilic oesophagitis and oesophageal motility disorders are among the most common diseases accompanying oesophageal eosinophilia. They have similarities and their limits are frequently not well defined. This article reviews the main characteristics relating to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406026/ https://www.ncbi.nlm.nih.gov/pubmed/32818156 http://dx.doi.org/10.1136/bmjpo-2020-000680 |
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author | Diaz-Oliva, Sarah Esther Aguilera-Matos, Idalmis Villa Jiménez, Oscar Manuel Escobedo, Angel A |
author_facet | Diaz-Oliva, Sarah Esther Aguilera-Matos, Idalmis Villa Jiménez, Oscar Manuel Escobedo, Angel A |
author_sort | Diaz-Oliva, Sarah Esther |
collection | PubMed |
description | Gastro-oesophageal reflux disease, eosinophilic oesophagitis and oesophageal motility disorders are among the most common diseases accompanying oesophageal eosinophilia. They have similarities and their limits are frequently not well defined. This article reviews the main characteristics relating to their similarities and differences, highlighting existing controversies among these diseases, in addition to current knowledge. In the case of a patient with symptoms of oesophageal dysfunction, it is suggested to carry out an integral analysis of the clinical features and diagnostic test results, including histology, while individualising each case before confirming a definitive diagnosis. Future investigation in paediatric patients is necessary to assess eosinophilic infiltration in the various layers of the oesophageal tissue, along with its clinical and pathophysiological implications. |
format | Online Article Text |
id | pubmed-7406026 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-74060262020-08-17 Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear? Diaz-Oliva, Sarah Esther Aguilera-Matos, Idalmis Villa Jiménez, Oscar Manuel Escobedo, Angel A BMJ Paediatr Open Review Gastro-oesophageal reflux disease, eosinophilic oesophagitis and oesophageal motility disorders are among the most common diseases accompanying oesophageal eosinophilia. They have similarities and their limits are frequently not well defined. This article reviews the main characteristics relating to their similarities and differences, highlighting existing controversies among these diseases, in addition to current knowledge. In the case of a patient with symptoms of oesophageal dysfunction, it is suggested to carry out an integral analysis of the clinical features and diagnostic test results, including histology, while individualising each case before confirming a definitive diagnosis. Future investigation in paediatric patients is necessary to assess eosinophilic infiltration in the various layers of the oesophageal tissue, along with its clinical and pathophysiological implications. BMJ Publishing Group 2020-08-04 /pmc/articles/PMC7406026/ /pubmed/32818156 http://dx.doi.org/10.1136/bmjpo-2020-000680 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Review Diaz-Oliva, Sarah Esther Aguilera-Matos, Idalmis Villa Jiménez, Oscar Manuel Escobedo, Angel A Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear? |
title | Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear? |
title_full | Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear? |
title_fullStr | Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear? |
title_full_unstemmed | Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear? |
title_short | Oesophageal eosinophilia and oesophageal diseases in children: are the limits clear? |
title_sort | oesophageal eosinophilia and oesophageal diseases in children: are the limits clear? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406026/ https://www.ncbi.nlm.nih.gov/pubmed/32818156 http://dx.doi.org/10.1136/bmjpo-2020-000680 |
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