Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway

METHODS: Forty-four COVID-19 patients (severe/critical: N = 8, non-severe: N = 36) were examined by next generation sequencing (NGS) of nasopharyngeal test paper to observe the effect of novel coronavirus infection to the microbial composition in upper airway. RESULTS: In these nasopharyngeal test p...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhenguo, Hu, Xiaojun, Li, Zhonghe, Tu, Changli, Wang, Yiming, Pang, Pengfei, Zhang, Huitao, Zheng, Xiaobin, Liang, Yingjian, Shan, Hong, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406177/
https://www.ncbi.nlm.nih.gov/pubmed/32801801
http://dx.doi.org/10.2147/IDR.S259984
Descripción
Sumario:METHODS: Forty-four COVID-19 patients (severe/critical: N = 8, non-severe: N = 36) were examined by next generation sequencing (NGS) of nasopharyngeal test paper to observe the effect of novel coronavirus infection to the microbial composition in upper airway. RESULTS: In these nasopharyngeal test paper samples, 38 kinds of bacteria, 10 kinds of viruses except SARS-CoV-2, nine kinds of fungi and three kinds of atypical pathogens had been found. There was some difference in microbial composition in the upper airway between severe and non-severe cases. SUMMARY: These results are important for us to study the effect of SARS-CoV-2 on the local microbial composition of upper airway and prevent opportunistic infection in severe patients.

Ejemplares similares