Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway

METHODS: Forty-four COVID-19 patients (severe/critical: N = 8, non-severe: N = 36) were examined by next generation sequencing (NGS) of nasopharyngeal test paper to observe the effect of novel coronavirus infection to the microbial composition in upper airway. RESULTS: In these nasopharyngeal test p...

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Autores principales: Wang, Zhenguo, Hu, Xiaojun, Li, Zhonghe, Tu, Changli, Wang, Yiming, Pang, Pengfei, Zhang, Huitao, Zheng, Xiaobin, Liang, Yingjian, Shan, Hong, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406177/
https://www.ncbi.nlm.nih.gov/pubmed/32801801
http://dx.doi.org/10.2147/IDR.S259984
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author Wang, Zhenguo
Hu, Xiaojun
Li, Zhonghe
Tu, Changli
Wang, Yiming
Pang, Pengfei
Zhang, Huitao
Zheng, Xiaobin
Liang, Yingjian
Shan, Hong
Liu, Jing
author_facet Wang, Zhenguo
Hu, Xiaojun
Li, Zhonghe
Tu, Changli
Wang, Yiming
Pang, Pengfei
Zhang, Huitao
Zheng, Xiaobin
Liang, Yingjian
Shan, Hong
Liu, Jing
author_sort Wang, Zhenguo
collection PubMed
description METHODS: Forty-four COVID-19 patients (severe/critical: N = 8, non-severe: N = 36) were examined by next generation sequencing (NGS) of nasopharyngeal test paper to observe the effect of novel coronavirus infection to the microbial composition in upper airway. RESULTS: In these nasopharyngeal test paper samples, 38 kinds of bacteria, 10 kinds of viruses except SARS-CoV-2, nine kinds of fungi and three kinds of atypical pathogens had been found. There was some difference in microbial composition in the upper airway between severe and non-severe cases. SUMMARY: These results are important for us to study the effect of SARS-CoV-2 on the local microbial composition of upper airway and prevent opportunistic infection in severe patients.
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spelling pubmed-74061772020-08-14 Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway Wang, Zhenguo Hu, Xiaojun Li, Zhonghe Tu, Changli Wang, Yiming Pang, Pengfei Zhang, Huitao Zheng, Xiaobin Liang, Yingjian Shan, Hong Liu, Jing Infect Drug Resist Short Report METHODS: Forty-four COVID-19 patients (severe/critical: N = 8, non-severe: N = 36) were examined by next generation sequencing (NGS) of nasopharyngeal test paper to observe the effect of novel coronavirus infection to the microbial composition in upper airway. RESULTS: In these nasopharyngeal test paper samples, 38 kinds of bacteria, 10 kinds of viruses except SARS-CoV-2, nine kinds of fungi and three kinds of atypical pathogens had been found. There was some difference in microbial composition in the upper airway between severe and non-severe cases. SUMMARY: These results are important for us to study the effect of SARS-CoV-2 on the local microbial composition of upper airway and prevent opportunistic infection in severe patients. Dove 2020-07-31 /pmc/articles/PMC7406177/ /pubmed/32801801 http://dx.doi.org/10.2147/IDR.S259984 Text en © 2020 Wang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Short Report
Wang, Zhenguo
Hu, Xiaojun
Li, Zhonghe
Tu, Changli
Wang, Yiming
Pang, Pengfei
Zhang, Huitao
Zheng, Xiaobin
Liang, Yingjian
Shan, Hong
Liu, Jing
Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway
title Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway
title_full Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway
title_fullStr Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway
title_full_unstemmed Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway
title_short Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway
title_sort effect of sars-cov-2 infection on the microbial composition of upper airway
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406177/
https://www.ncbi.nlm.nih.gov/pubmed/32801801
http://dx.doi.org/10.2147/IDR.S259984
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