Daughterless, the Drosophila orthologue of TCF4, is required for associative learning and maintenance of the synaptic proteome

Mammalian transcription factor 4 (TCF4) has been linked to schizophrenia and intellectual disabilities, such as Pitt–Hopkins syndrome (PTHS). Here, we show that similarly to mammalian TCF4, fruit fly orthologue Daughterless (Da) is expressed widely in the Drosophila brain. Furthermore, silencing of...

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Detalles Bibliográficos
Autores principales: Tamberg, Laura, Jaago, Mariliis, Säälik, Kristi, Sirp, Alex, Tuvikene, Jürgen, Shubina, Anastassia, Kiir, Carl Sander, Nurm, Kaja, Sepp, Mari, Timmusk, Tõnis, Palgi, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406316/
https://www.ncbi.nlm.nih.gov/pubmed/32641419
http://dx.doi.org/10.1242/dmm.042747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406316/
https://www.ncbi.nlm.nih.gov/pubmed/32641419
http://dx.doi.org/10.1242/dmm.042747

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