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Daughterless, the Drosophila orthologue of TCF4, is required for associative learning and maintenance of the synaptic proteome
Mammalian transcription factor 4 (TCF4) has been linked to schizophrenia and intellectual disabilities, such as Pitt–Hopkins syndrome (PTHS). Here, we show that similarly to mammalian TCF4, fruit fly orthologue Daughterless (Da) is expressed widely in the Drosophila brain. Furthermore, silencing of...
Autores principales: | Tamberg, Laura, Jaago, Mariliis, Säälik, Kristi, Sirp, Alex, Tuvikene, Jürgen, Shubina, Anastassia, Kiir, Carl Sander, Nurm, Kaja, Sepp, Mari, Timmusk, Tõnis, Palgi, Mari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406316/ https://www.ncbi.nlm.nih.gov/pubmed/32641419 http://dx.doi.org/10.1242/dmm.042747 |
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