The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation

Adult hematopoietic stem cells (HSCs) are rare multipotent cells in bone marrow that are responsible for generating all blood cell types. HSCs are a heterogeneous group of cells with high plasticity, in part, conferred by epigenetic mechanisms. PHF19, a subunit of the Polycomb repressive complex 2 (...

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Detalles Bibliográficos
Autores principales: Vizán, Pedro, Gutiérrez, Arantxa, Espejo, Isabel, García-Montolio, Marc, Lange, Martin, Carretero, Ana, Lafzi, Atefeh, de Andrés-Aguayo, Luisa, Blanco, Enrique, Thambyrajah, Roshana, Graf, Thomas, Heyn, Holger, Bigas, Anna, Di Croce, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406347/
https://www.ncbi.nlm.nih.gov/pubmed/32821835
http://dx.doi.org/10.1126/sciadv.abb2745

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