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Neohesperidin enhances PGC-1α-mediated mitochondrial biogenesis and alleviates hepatic steatosis in high fat diet fed mice

BACKGROUNDS: Mitochondria plays a critical role in the development and pathogenesis of nonalcoholic fatty liver disease (NAFLD). Neohesperidin (NHP) could lower blood glucose and prevent obesity in mice. However, the direct effect of NHP on hepatic steatosis has not been reported. METHODS: Mice were...

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Detalles Bibliográficos
Autores principales:	Wang, Si-wei, Sheng, Hao, Bai, Yong-feng, Weng, Yuan-yuan, Fan, Xue-yu, Lou, Li-jun, Zhang, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406515/ https://www.ncbi.nlm.nih.gov/pubmed/32759940 http://dx.doi.org/10.1038/s41387-020-00130-3

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