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CRISPR/Cas13d-Mediated Microbial RNA Knockdown

RNA-guided and RNA-targeting type IV-D CRISPR/Cas systems (CRISPR/Cas13d) have recently been identified and employed for efficient and specific RNA knockdown in mammalian and plant cells. Cas13d possesses dual RNase activities and is capable of processing CRISPR arrays and cleaving target RNAs in a...

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Detalles Bibliográficos
Autores principales:	Zhang, Kun, Zhang, Zhihui, Kang, Jianan, Chen, Jiuzhou, Liu, Jiao, Gao, Ning, Fan, Liwen, Zheng, Ping, Wang, Yu, Sun, Jibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406568/ https://www.ncbi.nlm.nih.gov/pubmed/32850723 http://dx.doi.org/10.3389/fbioe.2020.00856

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