CRISPR/Cas: a potential gene-editing tool in the nervous system

The rapidly developmental RNA-guided CRISPR/Cas system is a powerful tool for RNA and DNA editing in a variety of cells from different species and makes a great contribution to gene function research, disease model generation and gene therapy development in the past few years. The ease of use, low c...

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Detalles Bibliográficos
Autores principales: Gao, Yanxia, Gao, Kexin, Yang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406588/
https://www.ncbi.nlm.nih.gov/pubmed/32761306
http://dx.doi.org/10.1186/s13619-020-00044-6
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author Gao, Yanxia
Gao, Kexin
Yang, Hui
author_facet Gao, Yanxia
Gao, Kexin
Yang, Hui
author_sort Gao, Yanxia
collection PubMed
description The rapidly developmental RNA-guided CRISPR/Cas system is a powerful tool for RNA and DNA editing in a variety of cells from different species and makes a great contribution to gene function research, disease model generation and gene therapy development in the past few years. The ease of use, low cost and high efficiency of CRISPR/Cas make it commonly used in various conditions. In this review, we introduce the CRISPR/Cas system and its diverse applications in nervous system briefly, which provides a better understanding for its potential application values.
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spelling pubmed-74065882020-08-17 CRISPR/Cas: a potential gene-editing tool in the nervous system Gao, Yanxia Gao, Kexin Yang, Hui Cell Regen Review The rapidly developmental RNA-guided CRISPR/Cas system is a powerful tool for RNA and DNA editing in a variety of cells from different species and makes a great contribution to gene function research, disease model generation and gene therapy development in the past few years. The ease of use, low cost and high efficiency of CRISPR/Cas make it commonly used in various conditions. In this review, we introduce the CRISPR/Cas system and its diverse applications in nervous system briefly, which provides a better understanding for its potential application values. Springer Singapore 2020-08-06 /pmc/articles/PMC7406588/ /pubmed/32761306 http://dx.doi.org/10.1186/s13619-020-00044-6 Text en © The Author(s) 2021, corrected publication 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Gao, Yanxia
Gao, Kexin
Yang, Hui
CRISPR/Cas: a potential gene-editing tool in the nervous system
title CRISPR/Cas: a potential gene-editing tool in the nervous system
title_full CRISPR/Cas: a potential gene-editing tool in the nervous system
title_fullStr CRISPR/Cas: a potential gene-editing tool in the nervous system
title_full_unstemmed CRISPR/Cas: a potential gene-editing tool in the nervous system
title_short CRISPR/Cas: a potential gene-editing tool in the nervous system
title_sort crispr/cas: a potential gene-editing tool in the nervous system
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406588/
https://www.ncbi.nlm.nih.gov/pubmed/32761306
http://dx.doi.org/10.1186/s13619-020-00044-6
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AT yanghui crisprcasapotentialgeneeditingtoolinthenervoussystem

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