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Targeting B7-H3 Immune Checkpoint With Chimeric Antigen Receptor-Engineered Natural Killer Cells Exhibits Potent Cytotoxicity Against Non-Small Cell Lung Cancer

Chimeric antigen receptor (CAR)-modified natural killer (NK) cell therapy represents a kind of promising anti-cancer treatment because CAR renders NK cells activation and recognition specificity toward tumor cells. An immune checkpoint molecule, B7-H3, plays an inhibitory role in modulation of NK ce...

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Detalles Bibliográficos
Autores principales:	Yang, Shuo, Cao, Bihui, Zhou, Guangyu, Zhu, Lipeng, Wang, Lu, Zhang, Li, Kwok, Hang Fai, Zhang, Zhenfeng, Zhao, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406658/ https://www.ncbi.nlm.nih.gov/pubmed/32848731 http://dx.doi.org/10.3389/fphar.2020.01089

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