COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition

PDE4 inhibition reduces sputum eosinophils in those COPD patients with higher eosinophil counts. This evidence supports an effect of PDE4 inhibitors on eosinophilic inflammation. https://bit.ly/3airXw7

Detalles Bibliográficos
Autores principales: Singh, Dave, Watz, Henrik, Beeh, Kai Michael, Kornmann, Oliver, Leaker, Brian, Colgan, Brendan, Lucci, Germano, Emirova, Aida, Nandeuil, Marie Anna, Santoro, Debora, Balzano, Deborah, Govoni, Mirco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Agora
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406856/
https://www.ncbi.nlm.nih.gov/pubmed/32341106
http://dx.doi.org/10.1183/13993003.00237-2020
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author Singh, Dave
Watz, Henrik
Beeh, Kai Michael
Kornmann, Oliver
Leaker, Brian
Colgan, Brendan
Lucci, Germano
Emirova, Aida
Nandeuil, Marie Anna
Santoro, Debora
Balzano, Deborah
Govoni, Mirco
author_facet Singh, Dave
Watz, Henrik
Beeh, Kai Michael
Kornmann, Oliver
Leaker, Brian
Colgan, Brendan
Lucci, Germano
Emirova, Aida
Nandeuil, Marie Anna
Santoro, Debora
Balzano, Deborah
Govoni, Mirco
author_sort Singh, Dave
collection PubMed
description PDE4 inhibition reduces sputum eosinophils in those COPD patients with higher eosinophil counts. This evidence supports an effect of PDE4 inhibitors on eosinophilic inflammation. https://bit.ly/3airXw7
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spelling pubmed-74068562020-08-10 COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition Singh, Dave Watz, Henrik Beeh, Kai Michael Kornmann, Oliver Leaker, Brian Colgan, Brendan Lucci, Germano Emirova, Aida Nandeuil, Marie Anna Santoro, Debora Balzano, Deborah Govoni, Mirco Eur Respir J Agora PDE4 inhibition reduces sputum eosinophils in those COPD patients with higher eosinophil counts. This evidence supports an effect of PDE4 inhibitors on eosinophilic inflammation. https://bit.ly/3airXw7 European Respiratory Society 2020-08-06 /pmc/articles/PMC7406856/ /pubmed/32341106 http://dx.doi.org/10.1183/13993003.00237-2020 Text en Copyright ©ERS 2020 http://creativecommons.org/licenses/by-nc/4.0/This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
spellingShingle Agora
Singh, Dave
Watz, Henrik
Beeh, Kai Michael
Kornmann, Oliver
Leaker, Brian
Colgan, Brendan
Lucci, Germano
Emirova, Aida
Nandeuil, Marie Anna
Santoro, Debora
Balzano, Deborah
Govoni, Mirco
COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition
title COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition
title_full COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition
title_fullStr COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition
title_full_unstemmed COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition
title_short COPD sputum eosinophils: relationship to blood eosinophils and the effect of inhaled PDE4 inhibition
title_sort copd sputum eosinophils: relationship to blood eosinophils and the effect of inhaled pde4 inhibition
topic Agora
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406856/
https://www.ncbi.nlm.nih.gov/pubmed/32341106
http://dx.doi.org/10.1183/13993003.00237-2020
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