Interleukin-6 promotes proliferative vitreoretinopathy by inducing epithelial-mesenchymal transition via the JAK1/STAT3 signaling pathway

PURPOSE: Interleukin-6 (IL-6) is elevated in intraocular fluid from eyes with proliferative vitreoretinopathy (PVR), but the exact role of the cytokine is still unclear. We investigated the function and mechanism of IL-6 in retinal pigment epithelium (RPE) cell biology in vitro and in a mouse model...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoyun, Yang, Weimin, Deng, Xiaoqian, Ye, Shaobi, Xiao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406861/
https://www.ncbi.nlm.nih.gov/pubmed/32818015

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