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Loss of histone H4 lysine 20 trimethylation in osteosarcoma is associated with aberrant expression ofhistone methyltransferase SUV420H2

Epigenetic modifications of histones have crucial roles in various types of cancers. The aberrant trimethylation of histone H4 at lysine 20 (H4K20) has been implicated in carcinogenesis. At present, the status of trimethylation at H4k20 (H4K20me3) in osteosarcoma (OS), the predominant bone cancer in...

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Detalles Bibliográficos
Autores principales:	Piao, Lianhua, Yuan, Xiaofeng, Wang, Luhui, Xu, Xiaoshuang, Zhuang, Ming, Li, Jinggao, Kong, Ren, Liu, Zhiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406877/ https://www.ncbi.nlm.nih.gov/pubmed/32774499 http://dx.doi.org/10.3892/ol.2020.11887

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