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Evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation

OBJECTIVE: The objective of this study is to compare the first-trimester hemogram parameters [neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR)] of pregnant women complicated by intrauterine growth retardation (IUGR) and normal pregnant women. MATERIALS AND METHODS: We retrospect...

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Autores principales: Tolunay, Harun Egemen, Eroğlu, Hasan, Varlı, Erol Nadi, Akşar, Mustafa, Şahin, Dilek, Yücel, Aykan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406896/
https://www.ncbi.nlm.nih.gov/pubmed/32850183
http://dx.doi.org/10.4274/tjod.galenos.2020.81592
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author Tolunay, Harun Egemen
Eroğlu, Hasan
Varlı, Erol Nadi
Akşar, Mustafa
Şahin, Dilek
Yücel, Aykan
author_facet Tolunay, Harun Egemen
Eroğlu, Hasan
Varlı, Erol Nadi
Akşar, Mustafa
Şahin, Dilek
Yücel, Aykan
author_sort Tolunay, Harun Egemen
collection PubMed
description OBJECTIVE: The objective of this study is to compare the first-trimester hemogram parameters [neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR)] of pregnant women complicated by intrauterine growth retardation (IUGR) and normal pregnant women. MATERIALS AND METHODS: We retrospectively evaluated the medical records of pregnant women (n=50) complicated with IUGR and pregnant women in the control group (n=50). RESULTS: The first-trimester NLR and PLR values of the pregnant women complicated by IUGR were 6.59±1.12 and 117.2±16.00, respectively. The first-trimester NLR and PLR values of the pregnant women in the control group were 2.84±0.55 and 112.80±13.01, respectively. There was a statistically significant difference between the two groups with respect to NLR (p<0.001). CONCLUSION: Pregnancies complicated by IUGR have high neonatal mortality and morbidity rates. Therefore, the early diagnosis of disease and appropriate management are extremely crucial for both fetal and maternal prognoses. High NLR values in the first trimester may contribute to the early diagnosis of IUGR.
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spelling pubmed-74068962020-08-25 Evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation Tolunay, Harun Egemen Eroğlu, Hasan Varlı, Erol Nadi Akşar, Mustafa Şahin, Dilek Yücel, Aykan Turk J Obstet Gynecol Clinical Investigation OBJECTIVE: The objective of this study is to compare the first-trimester hemogram parameters [neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR)] of pregnant women complicated by intrauterine growth retardation (IUGR) and normal pregnant women. MATERIALS AND METHODS: We retrospectively evaluated the medical records of pregnant women (n=50) complicated with IUGR and pregnant women in the control group (n=50). RESULTS: The first-trimester NLR and PLR values of the pregnant women complicated by IUGR were 6.59±1.12 and 117.2±16.00, respectively. The first-trimester NLR and PLR values of the pregnant women in the control group were 2.84±0.55 and 112.80±13.01, respectively. There was a statistically significant difference between the two groups with respect to NLR (p<0.001). CONCLUSION: Pregnancies complicated by IUGR have high neonatal mortality and morbidity rates. Therefore, the early diagnosis of disease and appropriate management are extremely crucial for both fetal and maternal prognoses. High NLR values in the first trimester may contribute to the early diagnosis of IUGR. Galenos Publishing 2020-06 2020-07-29 /pmc/articles/PMC7406896/ /pubmed/32850183 http://dx.doi.org/10.4274/tjod.galenos.2020.81592 Text en ©Copyright 2020 by Turkish Society of Obstetrics and Gynecology | Turkish Journal of Obstetrics and Gynecology published by Galenos Publishing House. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Investigation
Tolunay, Harun Egemen
Eroğlu, Hasan
Varlı, Erol Nadi
Akşar, Mustafa
Şahin, Dilek
Yücel, Aykan
Evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation
title Evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation
title_full Evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation
title_fullStr Evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation
title_full_unstemmed Evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation
title_short Evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation
title_sort evaluation of first-trimester neutrophil-lymphocyte ratio and platelet-lymphocyte ratio values in pregnancies complicated by intrauterine growth retardation
topic Clinical Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406896/
https://www.ncbi.nlm.nih.gov/pubmed/32850183
http://dx.doi.org/10.4274/tjod.galenos.2020.81592
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