Attenuation of ataxia telangiectasia mutated signalling mitigates age‐associated intervertebral disc degeneration

Previously, we reported that persistent DNA damage accelerates ageing of the spine, but the mechanisms behind this process are not well understood. Ataxia telangiectasia mutated (ATM) is a protein kinase involved in the DNA damage response, which controls cell fate, including cell death. To test the...

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Detalles Bibliográficos
Autores principales: Han, Yingchao, Zhou, Chao‐Ming, Shen, Hongxing, Tan, Jun, Dong, Qing, Zhang, Lei, McGowan, Sara J., Zhao, Jing, Sowa, Gwendolyn A., Kang, James D., Niedernhofer, Laura J., Robbins, Paul D., Vo, Nam N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406969/
https://www.ncbi.nlm.nih.gov/pubmed/32567210
http://dx.doi.org/10.1111/acel.13162

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