Synthetic DNA Delivery of an Engineered Arginase Enzyme Can Modulate Specific Immunity In Vivo

Arginase is a complex and unique enzyme that plays diverse roles in health and disease. By metabolizing arginine, it can shape the outcome of innate and adaptive immune responses. The immunomodulatory capabilities of arginase could potentially be applied for local immunosuppression or induction of i...

Descripción completa

Detalles Bibliográficos
Autores principales: Khoshnejad, Makan, Perales-Puchalt, Alfredo, Dia, Yaya, Xiao, Peng, Patel, Ami, Xu, Ziyang, Zhu, Xizhou, Yun, Kun, Baboo, Ishana, Qureshi, Rehman, Humeau, Laurent, Muthumani, Kar, Weiner, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406982/
https://www.ncbi.nlm.nih.gov/pubmed/32802913
http://dx.doi.org/10.1016/j.omtm.2020.05.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7406982/
https://www.ncbi.nlm.nih.gov/pubmed/32802913
http://dx.doi.org/10.1016/j.omtm.2020.05.025

Ejemplares similares