Cargando…
Abnormal Expression of BTLA and CTLA-4 Immune Checkpoint Molecules in Chronic Lymphocytic Leukemia Patients
Chronic lymphocytic leukemia (CLL) is characterized by the peripheral accumulation of neoplastic B cells and is frequently complicated by the systemic immunosuppression associated with an impairment in B and T lymphocyte activation. We hypothesized that the expression of immune checkpoint suppressor...
Autores principales: | Karabon, L., Partyka, A., Ciszak, L., Pawlak-Adamska, E., Tomkiewicz, A., Bojarska-Junak, A., Roliński, J., Wołowiec, D., Wrobel, T., Frydecka, I., Kosmaczewska, A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407019/ https://www.ncbi.nlm.nih.gov/pubmed/32775467 http://dx.doi.org/10.1155/2020/6545921 |
Ejemplares similares
-
BTLA Expression in CLL: Epigenetic Regulation and Impact on CLL B Cell Proliferation and Ability to IL-4 Production
por: Karabon, Lidia, et al.
Publicado: (2021) -
Intragenic Variations in BTLA Gene Influence mRNA Expression of BTLA Gene in Chronic Lymphocytic Leukemia Patients and Confer Susceptibility to Chronic Lymphocytic Leukemia
por: Karabon, Lidia, et al.
Publicado: (2016) -
Patients with chronic lymphocytic leukaemia (CLL) differ in the pattern of CTLA-4 expression on CLL cells: the possible implications for immunotherapy with CTLA-4 blocking antibody
por: Ciszak, Lidia, et al.
Publicado: (2015) -
CTLA-4 affects expression of key cell cycle regulators of G0/G1 phase in neoplastic lymphocytes from patients with chronic lymphocytic leukaemia
por: Ciszak, Lidia, et al.
Publicado: (2015) -
Alterations of the expression of T-cell-related costimulatory CD28 and downregulatory CD152 (CTLA-4) molecules in patients with B-cell chronic lymphocytic leukaemia
por: Frydecka, I, et al.
Publicado: (2004)