HIV Vpr Modulates the Host DNA Damage Response at Two Independent Steps to Damage DNA and Repress Double-Strand DNA Break Repair

The DNA damage response (DDR) is a signaling cascade that is vital to ensuring the fidelity of the host genome in the presence of genotoxic stress. Growing evidence has emphasized the importance of both activation and repression of the host DDR by diverse DNA and RNA viruses. Previous work has shown...

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Detalles Bibliográficos
Autores principales: Li, Donna, Lopez, Andrew, Sandoval, Carina, Nichols Doyle, Randilea, Fregoso, Oliver I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407082/
https://www.ncbi.nlm.nih.gov/pubmed/32753492
http://dx.doi.org/10.1128/mBio.00940-20

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