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Mechanism and Function of Antiviral RNA Interference in Mice

Distinct mammalian RNA viruses trigger Dicer-mediated production of virus-derived small-interfering RNAs (vsiRNA) and encode unrelated proteins to suppress vsiRNA biogenesis. However, the mechanism and function of the mammalian RNA interference (RNAi) response are poorly understood. Here, we charact...

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Detalles Bibliográficos
Autores principales: Han, Qingxia, Chen, Gang, Wang, Jinyan, Jee, David, Li, Wan-Xiang, Lai, Eric C., Ding, Shou-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407090/
https://www.ncbi.nlm.nih.gov/pubmed/32753500
http://dx.doi.org/10.1128/mBio.03278-19