Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequ...

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Detalles Bibliográficos
Autores principales: van der Beek, Justine N., Geller, James I., de Krijger, Ronald R., Graf, Norbert, Pritchard-Jones, Kathy, Drost, Jarno, Verschuur, Arnauld C., Murphy, Dermot, Ray, Satyajit, Spreafico, Filippo, Dzhuma, Kristina, Littooij, Annemieke S., Selle, Barbara, Tytgat, Godelieve A. M., van den Heuvel-Eibrink, Marry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407101/
https://www.ncbi.nlm.nih.gov/pubmed/32635225
http://dx.doi.org/10.3390/cancers12071776
Descripción
Sumario:Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequently occurring adult types of RCC. However, published pediatric data suggest that clinical, molecular and histological characteristics of pediatric RCC differ from adult RCC. This paper summarizes reported series consisting of ≥10 RCC pediatric patients in order to create an up-to-date overview of the clinical and histopathological characteristics, treatment and outcome of pediatric RCC patients.

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