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Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequ...

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Autores principales: van der Beek, Justine N., Geller, James I., de Krijger, Ronald R., Graf, Norbert, Pritchard-Jones, Kathy, Drost, Jarno, Verschuur, Arnauld C., Murphy, Dermot, Ray, Satyajit, Spreafico, Filippo, Dzhuma, Kristina, Littooij, Annemieke S., Selle, Barbara, Tytgat, Godelieve A. M., van den Heuvel-Eibrink, Marry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407101/
https://www.ncbi.nlm.nih.gov/pubmed/32635225
http://dx.doi.org/10.3390/cancers12071776
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author van der Beek, Justine N.
Geller, James I.
de Krijger, Ronald R.
Graf, Norbert
Pritchard-Jones, Kathy
Drost, Jarno
Verschuur, Arnauld C.
Murphy, Dermot
Ray, Satyajit
Spreafico, Filippo
Dzhuma, Kristina
Littooij, Annemieke S.
Selle, Barbara
Tytgat, Godelieve A. M.
van den Heuvel-Eibrink, Marry M.
author_facet van der Beek, Justine N.
Geller, James I.
de Krijger, Ronald R.
Graf, Norbert
Pritchard-Jones, Kathy
Drost, Jarno
Verschuur, Arnauld C.
Murphy, Dermot
Ray, Satyajit
Spreafico, Filippo
Dzhuma, Kristina
Littooij, Annemieke S.
Selle, Barbara
Tytgat, Godelieve A. M.
van den Heuvel-Eibrink, Marry M.
author_sort van der Beek, Justine N.
collection PubMed
description Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequently occurring adult types of RCC. However, published pediatric data suggest that clinical, molecular and histological characteristics of pediatric RCC differ from adult RCC. This paper summarizes reported series consisting of ≥10 RCC pediatric patients in order to create an up-to-date overview of the clinical and histopathological characteristics, treatment and outcome of pediatric RCC patients.
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spelling pubmed-74071012020-08-11 Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review van der Beek, Justine N. Geller, James I. de Krijger, Ronald R. Graf, Norbert Pritchard-Jones, Kathy Drost, Jarno Verschuur, Arnauld C. Murphy, Dermot Ray, Satyajit Spreafico, Filippo Dzhuma, Kristina Littooij, Annemieke S. Selle, Barbara Tytgat, Godelieve A. M. van den Heuvel-Eibrink, Marry M. Cancers (Basel) Review Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequently occurring adult types of RCC. However, published pediatric data suggest that clinical, molecular and histological characteristics of pediatric RCC differ from adult RCC. This paper summarizes reported series consisting of ≥10 RCC pediatric patients in order to create an up-to-date overview of the clinical and histopathological characteristics, treatment and outcome of pediatric RCC patients. MDPI 2020-07-03 /pmc/articles/PMC7407101/ /pubmed/32635225 http://dx.doi.org/10.3390/cancers12071776 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
van der Beek, Justine N.
Geller, James I.
de Krijger, Ronald R.
Graf, Norbert
Pritchard-Jones, Kathy
Drost, Jarno
Verschuur, Arnauld C.
Murphy, Dermot
Ray, Satyajit
Spreafico, Filippo
Dzhuma, Kristina
Littooij, Annemieke S.
Selle, Barbara
Tytgat, Godelieve A. M.
van den Heuvel-Eibrink, Marry M.
Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review
title Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review
title_full Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review
title_fullStr Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review
title_full_unstemmed Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review
title_short Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review
title_sort characteristics and outcome of children with renal cell carcinoma: a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407101/
https://www.ncbi.nlm.nih.gov/pubmed/32635225
http://dx.doi.org/10.3390/cancers12071776
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