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Astrocyte- and Neuron-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Effect Complement-Mediated Neurotoxicity
We have previously shown that blood astrocytic-origin extracellular vesicles (AEVs) from Alzheimer’s disease (AD) patients contain high complement levels. To test the hypothesis that circulating EVs from AD patients can induce complement-mediated neurotoxicity involving Membrane Attack Complex (MAC)...
Autores principales: | Nogueras-Ortiz, Carlos J., Mahairaki, Vasiliki, Delgado-Peraza, Francheska, Das, Debamitra, Avgerinos, Konstantinos, Eren, Erden, Hentschel, Matthew, Goetzl, Edward J., Mattson, Mark P., Kapogiannis, Dimitrios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407141/ https://www.ncbi.nlm.nih.gov/pubmed/32635578 http://dx.doi.org/10.3390/cells9071618 |
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