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Toxicoproteomic Profiling of hPXR Transgenic Mice Treated with Rifampicin and Isoniazid

Tuberculosis is a global health threat that affects millions of people every year, and treatment-limiting toxicity remains a considerable source of treatment failure. Recent reports have characterized the nature of hPXR-mediated hepatotoxicity and the systemic toxicity of antitubercular drugs. The a...

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Detalles Bibliográficos
Autores principales: Brewer, Christopher Trent, Kodali, Kiran, Wu, Jing, Shaw, Timothy I., Peng, Junmin, Chen, Taosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407182/
https://www.ncbi.nlm.nih.gov/pubmed/32660103
http://dx.doi.org/10.3390/cells9071654

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