Oxygen-Dependent Accumulation of Purine DNA Lesions in Cockayne Syndrome Cells

Cockayne Syndrome (CS) is an autosomal recessive neurodegenerative premature aging disorder associated with defects in nucleotide excision repair (NER). Cells from CS patients, with mutations in CSA or CSB genes, present elevated levels of reactive oxygen species (ROS) and are defective in the repai...

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Detalles Bibliográficos
Autores principales: Krokidis, Marios G., D’Errico, Mariarosaria, Pascucci, Barbara, Parlanti, Eleonora, Masi, Annalisa, Ferreri, Carla, Chatgilialoglu, Chryssostomos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407219/
https://www.ncbi.nlm.nih.gov/pubmed/32664519
http://dx.doi.org/10.3390/cells9071671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407219/
https://www.ncbi.nlm.nih.gov/pubmed/32664519
http://dx.doi.org/10.3390/cells9071671

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