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Oxygen-Dependent Accumulation of Purine DNA Lesions in Cockayne Syndrome Cells
Cockayne Syndrome (CS) is an autosomal recessive neurodegenerative premature aging disorder associated with defects in nucleotide excision repair (NER). Cells from CS patients, with mutations in CSA or CSB genes, present elevated levels of reactive oxygen species (ROS) and are defective in the repai...
Autores principales: | Krokidis, Marios G., D’Errico, Mariarosaria, Pascucci, Barbara, Parlanti, Eleonora, Masi, Annalisa, Ferreri, Carla, Chatgilialoglu, Chryssostomos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407219/ https://www.ncbi.nlm.nih.gov/pubmed/32664519 http://dx.doi.org/10.3390/cells9071671 |
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