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EZH2 in Myeloid Malignancies

Our understanding of the significance of epigenetic dysregulation in the pathogenesis of myeloid malignancies has greatly advanced in the past decade. Enhancer of Zeste Homolog 2 (EZH2) is the catalytic core component of the Polycomb Repressive Complex 2 (PRC2), which is responsible for gene silenci...

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Detalles Bibliográficos
Autores principales: Rinke, Jenny, Chase, Andrew, Cross, Nicholas C. P., Hochhaus, Andreas, Ernst, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407223/
https://www.ncbi.nlm.nih.gov/pubmed/32650416
http://dx.doi.org/10.3390/cells9071639