Cargando…
VariantSpark: Cloud-based machine learning for association study of complex phenotype and large-scale genomic data
BACKGROUND: Many traits and diseases are thought to be driven by >1 gene (polygenic). Polygenic risk scores (PRS) hence expand on genome-wide association studies by taking multiple genes into account when risk models are built. However, PRS only considers the additive effect of individual genes b...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407261/ https://www.ncbi.nlm.nih.gov/pubmed/32761098 http://dx.doi.org/10.1093/gigascience/giaa077 |