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Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells

Despite significant efforts to improve pancreatic ductal adenocarcinoma (PDAC) clinical outcomes, overall survival remains dismal. The poor response to current therapies is partly due to the existence of pancreatic cancer stem cells (PaCSCs), which are efficient drivers of PDAC tumorigenesis, metast...

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Detalles Bibliográficos
Autores principales:	Cash, Timothy P., Alcalá, Sonia, Rico-Ferreira, María del Rosario, Hernández-Encinas, Elena, García, Jennifer, Albarrán, María Isabel, Valle, Sandra, Muñoz, Javier, Martínez-González, Sonia, Blanco-Aparicio, Carmen, Pastor, Joaquín, Serrano, Manuel, Sainz, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407272/ https://www.ncbi.nlm.nih.gov/pubmed/32635473 http://dx.doi.org/10.3390/cancers12071790

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