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Endothelial Cell Targeting by cRGD-Functionalized Polymeric Nanoparticles under Static and Flow Conditions
Since α(v)β(3) integrin is a key component of angiogenesis in health and disease, Arg-Gly-Asp (RGD) peptide-functionalized nanocarriers have been investigated as vehicles for targeted delivery of drugs to the α(v)β(3) integrin-overexpressing neovasculature of tumors. In this work, PEGylated nanopart...
Autores principales: | Martínez-Jothar, Lucía, Barendrecht, Arjan D., de Graaff, Anko M., Oliveira, Sabrina, van Nostrum, Cornelus F., Schiffelers, Raymond M., Hennink, Wim E., Fens, Marcel H. A. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407316/ https://www.ncbi.nlm.nih.gov/pubmed/32664364 http://dx.doi.org/10.3390/nano10071353 |
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