Cargando…
Microglia Purinoceptor P2Y6: An Emerging Therapeutic Target in CNS Diseases
The purinergic receptor P2Y6 is expressed in immune cells, including the microglia that are implicated in neurological disorders. Its ligand, UDP, is a signaling molecule that can serve as an “find-me” signal when released in significant quantities by damaged/dying cells. The binding of UDP by P2Y6R...
Autores principales: | Anwar, Shehata, Pons, Vincent, Rivest, Serge |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407337/ https://www.ncbi.nlm.nih.gov/pubmed/32630251 http://dx.doi.org/10.3390/cells9071595 |
Ejemplares similares
-
Beneficial Roles of Microglia and Growth Factors in MS, a Brief Review
por: Pons, Vincent, et al.
Publicado: (2020) -
P2RX7 Purinoceptor as a Therapeutic Target—The Second Coming?
por: Young, Chris N. J., et al.
Publicado: (2018) -
The P2 purinoceptors in prostate cancer
por: Wang, Zilin, et al.
Publicado: (2022) -
Purinoceptor: a novel target for hypertension
por: Li, Xuan, et al.
Publicado: (2022) -
Conditional genetic deletion of CSF1 receptor in microglia ameliorates the physiopathology of Alzheimer’s disease
por: Pons, Vincent, et al.
Publicado: (2021)