Cargando…

Bayesian and Machine Learning Models for Genomic Prediction of Anterior Cruciate Ligament Rupture in the Canine Model

Anterior cruciate ligament (ACL) rupture is a common, debilitating condition that leads to early-onset osteoarthritis and reduced quality of human life. ACL rupture is a complex disease with both genetic and environmental risk factors. Characterizing the genetic basis of ACL rupture would provide th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baker, Lauren A., Momen, Mehdi, Chan, Kore, Bollig, Nathan, Lopes, Fernando Brito, Rosa, Guilherme J. M., Todhunter, Rory J., Binversie, Emily E., Sample, Susannah J., Muir, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2020
Materias:	Genomic Prediction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407450/ https://www.ncbi.nlm.nih.gov/pubmed/32499222 http://dx.doi.org/10.1534/g3.120.401244

Ejemplares similares

Across-breed genetic investigation of canine hip dysplasia, elbow dysplasia, and anterior cruciate ligament rupture using whole-genome sequencing
por: Binversie, Emily E., et al.
Publicado: (2022)

Biologically Enhanced Genome-Wide Association Study Provides Further Evidence for Candidate Loci and Discovers Novel Loci That Influence Risk of Anterior Cruciate Ligament Rupture in a Dog Model
por: Baker, Lauren A., et al.
Publicado: (2021)

Multivariate genome-wide association analysis identifies novel and relevant variants associated with anterior cruciate ligament rupture risk in the dog model
por: Baker, Lauren A., et al.
Publicado: (2018)

Identification of genetic variants associated with anterior cruciate ligament rupture and AKC standard coat color in the Labrador Retriever
por: Lee, BT, et al.
Publicado: (2023)

Analysis of copy number variation in dogs implicates genomic structural variation in the development of anterior cruciate ligament rupture
por: Binversie, Emily E., et al.
Publicado: (2020)

Synovial fluid lubricin increases in spontaneous canine cruciate ligament rupture
por: Wang, Yuyan, et al.
Publicado: (2020)

Genome-wide association analysis in dogs implicates 99 loci as risk variants for anterior cruciate ligament rupture
por: Baker, Lauren A., et al.
Publicado: (2017)

Selection signature analyses and genome‐wide association reveal genomic hotspot regions that reflect differences between breeds of horse with contrasting risk of degenerative suspensory ligament desmitis
por: Momen, Mehdi, et al.
Publicado: (2022)

Radiographic and magnetic resonance imaging predicts severity of cruciate ligament fiber damage and synovitis in dogs with cranial cruciate ligament rupture
por: Sample, Susannah J., et al.
Publicado: (2017)

Genetic architecture and polygenic risk score prediction of degenerative suspensory ligament desmitis (DSLD) in the Peruvian Horse
por: Momen, Mehdi, et al.
Publicado: (2023)

Canine ACL rupture: a spontaneous large animal model of human ACL rupture
por: Binversie, Emily E., et al.
Publicado: (2022)

A Bayesian Genomic Multi-output Regressor Stacking Model for Predicting Multi-trait Multi-environment Plant Breeding Data
por: Montesinos-López, Osval A., et al.
Publicado: (2019)

Novel Bayesian Networks for Genomic Prediction of Developmental Traits in Biomass Sorghum
por: dos Santos, Jhonathan P. R., et al.
Publicado: (2019)

Prediction of HLA-A2 binding peptides using Bayesian network
por: Astakhov, Vadim, et al.
Publicado: (2005)

Predicting Longitudinal Traits Derived from High-Throughput Phenomics in Contrasting Environments Using Genomic Legendre Polynomials and B-Splines
por: Momen, Mehdi, et al.
Publicado: (2019)

TATPred: a Bayesian method for the identification of twin arginine translocation pathway signal sequences
por: Taylor, Paul D, et al.
Publicado: (2006)

Alpha helical trans-membrane proteins: Enhanced prediction using a Bayesian approach
por: Taylor, Paul D, et al.
Publicado: (2006)

Beta barrel trans-membrane proteins: Enhanced prediction using a Bayesian approach
por: Taylor, Paul D, et al.
Publicado: (2006)

Risk factors for cranial cruciate ligament rupture in dogs participating in canine agility
por: Sellon, Debra C., et al.
Publicado: (2022)

Heritability and genetic variance estimation of Osteosarcoma (OSA) in Irish Wolfhound, using deep pedigree information
por: Momen, Mehdi, et al.
Publicado: (2021)

Autologous Bone Marrow-Derived Mesenchymal Stem Cells Modulate Molecular Markers of Inflammation in Dogs with Cruciate Ligament Rupture
por: Muir, Peter, et al.
Publicado: (2016)

Use of a platelet-rich plasma-collagen scaffold as a bioenhanced repair treatment for management of partial cruciate ligament rupture in dogs
por: Sample, Susannah J., et al.
Publicado: (2018)

A Multiple-Trait Bayesian Variable Selection Regression Method for Integrating Phenotypic Causal Networks in Genome-Wide Association Studies
por: Wang, Zigui, et al.
Publicado: (2020)

A Benchmarking Between Deep Learning, Support Vector Machine and Bayesian Threshold Best Linear Unbiased Prediction for Predicting Ordinal Traits in Plant Breeding
por: Montesinos-López, Osval A., et al.
Publicado: (2019)

(Quasi) multitask support vector regression with heuristic hyperparameter optimization for whole-genome prediction of complex traits: a case study with carcass traits in broilers
por: Alves, Anderson Antonio Carvalho, et al.
Publicado: (2023)

Contralateral Cruciate Survival in Dogs with Unilateral Non-Contact Cranial Cruciate Ligament Rupture
por: Muir, Peter, et al.
Publicado: (2011)

Hidden markov model for the prediction of transmembrane proteins using MATLAB
por: Chaturvedi, Navaneet, et al.
Publicado: (2011)

Phantom Epistasis in Genomic Selection: On the Predictive Ability of Epistatic Models
por: Schrauf, Matías F., et al.
Publicado: (2020)

Multi-trait Genomic Prediction Model Increased the Predictive Ability for Agronomic and Malting Quality Traits in Barley (Hordeum vulgare L.)
por: Bhatta, Madhav, et al.
Publicado: (2020)

An ANN model for the identification of deleterious nsSNPs in tumor suppressor genes
por: Chandra, Vinod, et al.
Publicado: (2011)

Structure modeling and comparative genomics for epimerase enzyme (Gal10p)
por: Sharma, Ashwani, et al.
Publicado: (2010)

Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits
por: Montesinos-López, Abelardo, et al.
Publicado: (2020)

Benchmarking Parametric and Machine Learning Models for Genomic Prediction of Complex Traits
por: Azodi, Christina B., et al.
Publicado: (2019)

Opportunistic screening models for high-risk men and women to detect diastolic dysfunction and heart failure with preserved ejection fraction in the community
por: Gohar, Aisha, et al.
Publicado: (2018)

PCA-HPR: A principle component analysis model for human promoter recognition
por: Li, Xiaomeng, et al.
Publicado: (2008)

Validation and recalibration of the Framingham cardiovascular disease risk models in an Australian Indigenous cohort
por: Hua, Xinyang, et al.
Publicado: (2017)

A Multivariate Poisson Deep Learning Model for Genomic Prediction of Count Data
por: Montesinos-López, Osval Antonio, et al.
Publicado: (2020)

2D-QSAR model development and analysis on variant groups of anti-tuberculosis drugs
por: Dwivedi, Neeraja, et al.
Publicado: (2011)

An ANN-GA model based promoter prediction in Arabidopsis thaliana using tilling microarray data
por: Mishra, Hrishikesh, et al.
Publicado: (2011)

Extensions of BLUP Models for Genomic Prediction in Heterogeneous Populations: Application in a Diverse Switchgrass Sample
por: Ramstein, Guillaume P., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_g81mrrjq26keub2rgfauibojcu