Pro-Inflammatory Signaling Upregulates a Neurotoxic Conotoxin-Like Protein Encrypted Within Human Endogenous Retrovirus-K

Motor neuron degeneration and spinal cord demyelination are hallmark pathological events in Amyotrophic Lateral Sclerosis (ALS). Endogenous retrovirus-K (ERVK) expression has an established association with ALS neuropathology, with murine modeling pointing to a role for the ERVK envelope (env) gene...

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Detalles Bibliográficos
Autores principales: Di Curzio, Domenico, Gurm, Mamneet, Turnbull, Matthew, Nadeau, Marie-Josée, Meek, Breanna, Rempel, Julia D., Fineblit, Samuel, Jonasson, Michael, Hebert, Sherry, Ferguson-Parry, Jennifer, Douville, Renée N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407490/
https://www.ncbi.nlm.nih.gov/pubmed/32629888
http://dx.doi.org/10.3390/cells9071584

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