Cargando…

Evaluation of SS-31 as a Potential Therapeutic Target in the Treatment of Tendinopathy

OBJECTIVES: The purpose of this study is to investigate the therapeutic potential of SS-31, a target to improve mitochondria function for the treatment of tendinopathy using human tenocytes. METHODS: After IRB approval (IRB# 2018-0490), samples of non-injured hamstring tendon were obtained from 9 pa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szeto, Hazel, Zhang, Ying, Nakagawa, Yusuke, Carballo, Camila, Green, Samuel, Deng, Xianghua, Rodeo, Scott, Zhang, Xueying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407841/ http://dx.doi.org/10.1177/2325967120S00395

Ejemplares similares

Poster 100: Evaluation of SS-31 as a Potential Therapeutic in the Treatment of Tendinopathy
por: Szeto, Hazel, et al.
Publicado: (2022)

Poster 163: Evaluating the Role of Subacromial Impingement in Rotator Cuff Tendinopathy: Development and Analysis of a Novel Rat Model
por: Deng, Xianghua, et al.
Publicado: (2022)

Targeting Mitochondria by SS-31 Ameliorates the Whole Body Energy Status in Cancer- and Chemotherapy-Induced Cachexia
por: Ballarò, Riccardo, et al.
Publicado: (2021)

Regulation of gene expression in human tendinopathy
por: Jelinsky, Scott A, et al.
Publicado: (2011)

The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action
por: Mitchell, Wayne, et al.
Publicado: (2020)

SS-31, a Mitochondria-Targeting Peptide, Ameliorates Kidney Disease
por: Zhu, Yuexin, et al.
Publicado: (2022)

Synthesis, Characterization, and Specific Localization of Mitochondrial-Targeted Antioxidant Peptide SS31 Probe
por: He, Yuan, et al.
Publicado: (2021)

Targeting mitochondria in the aged cerebral vasculature with SS-31, a proteomic study of brain microvessels
por: Seman, Abigail, et al.
Publicado: (2023)

Toxicity of Neurons Treated with Herbicides and Neuroprotection by Mitochondria-Targeted Antioxidant SS31
por: Reddy, Tejaswini P., et al.
Publicado: (2011)

Poster 249: Evaluation of ACL Reconstruction Using a Bone-ACL-Bone Complex Allograft in a Rabbit Model
por: Havasy, Janice, et al.
Publicado: (2022)

Therapeutic Potential of Targeting ß-Arrestin
por: Bond, Richard A., et al.
Publicado: (2019)

GLI1 Deficiency Impairs the Tendon–Bone Healing after Anterior Cruciate Ligament Reconstruction: In Vivo Study Using Gli1-Transgenic Mice
por: Liu, Yake, et al.
Publicado: (2023)

Mitochondrial-Targeted Antioxidant Peptide SS31 Prevents RPE Cell Death under Oxidative Stress
por: He, Yuan, et al.
Publicado: (2022)

Mitochondria-Targeted Antioxidant SS-31 is a Potential Novel Ophthalmic Medication for Neuroprotection in Glaucoma
por: PANG, Yu, et al.
Publicado: (2015)

Therapeutic Roles of Tendon Stem/Progenitor Cells in Tendinopathy
por: Zhang, Xin, et al.
Publicado: (2016)

SS-31 peptide enables mitochondrial targeting drug delivery: a promising therapeutic alteration to prevent hair cell damage from aminoglycosides
por: Kuang, Xiao, et al.
Publicado: (2017)

Mitochondria-Targeted Peptide SS31 Attenuates Renal Tubulointerstitial Injury via Inhibiting Mitochondrial Fission in Diabetic Mice
por: Yang, Shi-kun, et al.
Publicado: (2019)

Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke
por: Yang, De-qing, et al.
Publicado: (2021)

The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis
por: Grosser, Joshua A., et al.
Publicado: (2021)

SS‐31 and NMN: Two paths to improve metabolism and function in aged hearts
por: Whitson, Jeremy A., et al.
Publicado: (2020)

Mechanisms and therapeutic prospects of mesenchymal stem cells-derived exosomes for tendinopathy
por: Zhang, Yuxiang, et al.
Publicado: (2023)

Evaluation and Management of Elbow Tendinopathy
por: Taylor, Samuel A., et al.
Publicado: (2012)

Combined Therapy with SS31 and Mitochondria Mitigates Myocardial Ischemia-Reperfusion Injury in Rats
por: Lee, Fan-Yen, et al.
Publicado: (2018)

Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice
por: Zhao, Weixing, et al.
Publicado: (2019)

Chronic administration of mitochondrion-targeted peptide SS-31 prevents atherosclerotic development in ApoE knockout mice fed Western diet
por: Zhang, Meng, et al.
Publicado: (2017)

Mitochondria-Targeted Antioxidant SS31 Prevents Amyloid Beta-Induced Mitochondrial Abnormalities and Synaptic Degeneration in Alzheimer’s Disease
por: Calkins, Marcus J., et al.
Publicado: (2012)

Tendinopathy in Sport
por: Ackermann, Paul W., et al.
Publicado: (2012)

Patellar Tendinopathy
por: Schwartz, Aaron, et al.
Publicado: (2015)

TENDINOPATHY AND OBESITY
por: CASTRO, Adham do Amaral e, et al.
Publicado: (2016)

Animal model for tendinopathy
por: Luo, Junchao, et al.
Publicado: (2023)

Platelet Membrane–Encapsulated MSNs Loaded with SS31 Peptide Alleviate Myocardial Ischemia-Reperfusion Injury
por: Zhang, Zaiyuan, et al.
Publicado: (2022)

Stem cell-based therapeutic strategies for rotator cuff tendinopathy
por: Wang, Zetao, et al.
Publicado: (2023)

Protective effects of SS31 on t-BHP induced oxidative damage in 661W cells
por: MA, WEI, et al.
Publicado: (2015)

SS-31 Provides Neuroprotection by Reversing Mitochondrial Dysfunction after Traumatic Brain Injury
por: Zhu, Yihao, et al.
Publicado: (2018)

Beneficial effects of SS-31 peptide on cardiac mitochondrial dysfunction in tafazzin knockdown mice
por: Russo, Silvia, et al.
Publicado: (2022)

Peptide SS-31 upregulates frataxin expression and improves the quality of mitochondria: implications in the treatment of Friedreich ataxia
por: Zhao, Hongting, et al.
Publicado: (2017)

Distinct Inflammatory Macrophage Populations Sequentially Infiltrate Bone‐to‐Tendon Interface Tissue After Anterior Cruciate Ligament (ACL) Reconstruction Surgery in Mice
por: Fujii, Takayuki, et al.
Publicado: (2022)

SS31 Alleviates Pressure Overload-Induced Heart Failure Caused by Sirt3-Mediated Mitochondrial Fusion
por: Suo, Mengying, et al.
Publicado: (2022)

Poster 130: Tendon-to-bone Healing in a CCR2 Knockout Mouse Model of Delayed Rotator Cuff Repair
por: Carballo, Camila, et al.
Publicado: (2022)

SS-31 Protects Liver from Ischemia-Reperfusion Injury via Modulating Macrophage Polarization
por: Shang, Longcheng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_uachcpperf9cv5g105s9s82ce6