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Neuronal-Specific Inhibition of Endoplasmic Reticulum Mg(2+)/Ca(2+) ATPase Ca(2+) Uptake in a Mixed Primary Hippocampal Culture Model of Status Epilepticus

Loss of intracellular calcium homeostasis is an established mechanism associated with neuronal dysfunction and status epilepticus. Sequestration of free cytosolic calcium into endoplasmic reticulum by Mg(2+)/Ca(2+) adenosinetriphosphatase (ATPase) is critical for maintenance of intracellular calcium...

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Detalles Bibliográficos
Autores principales: Deshpande, Laxmikant S., DeLorenzo, Robert J., Churn, Severn B., Parsons, J. Travis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407863/
https://www.ncbi.nlm.nih.gov/pubmed/32664397
http://dx.doi.org/10.3390/brainsci10070438

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