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Neuronal-Specific Inhibition of Endoplasmic Reticulum Mg(2+)/Ca(2+) ATPase Ca(2+) Uptake in a Mixed Primary Hippocampal Culture Model of Status Epilepticus
Loss of intracellular calcium homeostasis is an established mechanism associated with neuronal dysfunction and status epilepticus. Sequestration of free cytosolic calcium into endoplasmic reticulum by Mg(2+)/Ca(2+) adenosinetriphosphatase (ATPase) is critical for maintenance of intracellular calcium...
Autores principales: | Deshpande, Laxmikant S., DeLorenzo, Robert J., Churn, Severn B., Parsons, J. Travis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407863/ https://www.ncbi.nlm.nih.gov/pubmed/32664397 http://dx.doi.org/10.3390/brainsci10070438 |
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