Impairments of Synaptic Plasticity Induction Threshold and Network Oscillatory Activity in the Hippocampus Underlie Memory Deficits in a Non-Transgenic Mouse Model of Amyloidosis

In early Alzheimer disease (AD) models synaptic failures and upstreaming aberrant patterns of network synchronous activity result in hippocampal-dependent memory deficits. In such initial stage, soluble forms of Amyloid-β (Aβ) peptides have been shown to play a causal role. Among different Aβ specie...

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Detalles Bibliográficos
Autores principales: Mayordomo-Cava, Jennifer, Iborra-Lázaro, Guillermo, Djebari, Souhail, Temprano-Carazo, Sara, Sánchez-Rodríguez, Irene, Jeremic, Danko, Gruart, Agnès, Delgado-García, José María, Jiménez-Díaz, Lydia, Navarro-López, Juan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407959/
https://www.ncbi.nlm.nih.gov/pubmed/32698467
http://dx.doi.org/10.3390/biology9070175

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