Single Nucleotide Polymorphisms in MiRNA Binding Sites of Nucleotide Excision Repair-Related Genes Predict Clinical Benefit of Oxaliplatin in FOLFOXIRI Plus Bevacizumab: Analysis of the TRIBE Trial

Background: The nucleotide excision repair (NER) pathway participates in platinum-induced DNA damage repair. Single nucleotide polymorphisms (SNPs) in miRNA-binding sites in the NER genes RPA2 and GTF2H1 are associated with the risk of colorectal cancer (CRC). Here, we analyzed whether RPA2 and GTF2...

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Detalles Bibliográficos
Autores principales: Suenaga, Mitsukuni, Schirripa, Marta, Cao, Shu, Zhang, Wu, Yang, Dongyun, Cremolini, Chiara, Murgioni, Sabina, Lonardi, Sara, Ning, Yan, Okazaki, Satoshi, Berger, Martin D., Miyamoto, Yuji, Barzi, Afsaneh, Loupakis, Fotios, Falcone, Alfredo, Lenz, Heinz-Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408001/
https://www.ncbi.nlm.nih.gov/pubmed/32629861
http://dx.doi.org/10.3390/cancers12071742

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