miR-22-3p Negatively Affects Tumor Progression in T-Cell Acute Lymphoblastic Leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is a rare, aggressive disease arising from T-cell precursors. NOTCH1 plays an important role both in T-cell development and leukemia progression, and more than 60% of human T-ALLs harbor mutations in components of the NOTCH1 signaling pathway, leading to d...

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Detalles Bibliográficos
Autores principales: Saccomani, Valentina, Grassi, Angela, Piovan, Erich, Bongiovanni, Deborah, Di Martino, Ludovica, Minuzzo, Sonia, Tosello, Valeria, Zanovello, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408026/
https://www.ncbi.nlm.nih.gov/pubmed/32708470
http://dx.doi.org/10.3390/cells9071726

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