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Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology
Mitochondrial permeability transition (MPT) is the sudden loss in the permeability of the inner mitochondrial membrane (IMM) to low-molecular-weight solutes. Due to osmotic forces, MPT is paralleled by a massive influx of water into the mitochondrial matrix, eventually leading to the structural coll...
Autores principales: | Bonora, Massimo, Patergnani, Simone, Ramaccini, Daniela, Morciano, Giampaolo, Pedriali, Gaia, Kahsay, Asrat Endrias, Bouhamida, Esmaa, Giorgi, Carlotta, Wieckowski, Mariusz R., Pinton, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408088/ https://www.ncbi.nlm.nih.gov/pubmed/32635556 http://dx.doi.org/10.3390/biom10070998 |
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