Improving Nefiracetam Dissolution and Solubility Behavior Using a Cocrystallization Approach

In this work, we are the first to identify thirteen cocrystals of Nefiracetam, a poor water-soluble nootropic compound. Three of which were obtained with the biocompatible cocrystallization agents citric acid, oxalic acid, and zinc chloride. These latter have been fully structurally and physically c...

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Detalles Bibliográficos
Autores principales: Buol, Xavier, Robeyns, Koen, Caro Garrido, Camila, Tumanov, Nikolay, Collard, Laurent, Wouters, Johan, Leyssens, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408141/
https://www.ncbi.nlm.nih.gov/pubmed/32660115
http://dx.doi.org/10.3390/pharmaceutics12070653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408141/
https://www.ncbi.nlm.nih.gov/pubmed/32660115
http://dx.doi.org/10.3390/pharmaceutics12070653

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