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Interleukin-1β and Cancer
Within a tumor, IL-1β is produced and secreted by various cell types, such as immune cells, fibroblasts, or cancer cells. The IL1B gene is induced after “priming” of the cells and a second signal is required to allow IL-1β maturation by inflammasome-activated caspase-1. IL-1β is then released and le...
Autores principales: | Rébé, Cédric, Ghiringhelli, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408158/ https://www.ncbi.nlm.nih.gov/pubmed/32635472 http://dx.doi.org/10.3390/cancers12071791 |
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