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PLGA Microspheres of hGH of Preserved Native State Prepared Using a Self-Regulated Process
The challenges of formulating recombinant human growth hormone (rhGH) into sustained-release polymeric microspheres include two mutual causal factors, protein denaturing by the formulation process and severe initial burst release related with relative high dose. The stabilizers to protect the protei...
Autores principales: | Diana, Jebun Nessa, Tao, Ying, Du, Qiran, Wang, Meng, Kumar, Chinta Uday, Wu, Fei, Jin, Tuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408169/ https://www.ncbi.nlm.nih.gov/pubmed/32698347 http://dx.doi.org/10.3390/pharmaceutics12070683 |
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