Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance

In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%–85%), and minocycline cured 71% (95% CI, 54%–85%) of cases. T...

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Detalles Bibliográficos
Autores principales: Doyle, Michelle, Vodstrcil, Lenka A, Plummer, Erica L, Aguirre, Ivette, Fairley, Christopher K, Bradshaw, Catriona S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408185/
https://www.ncbi.nlm.nih.gov/pubmed/32782911
http://dx.doi.org/10.1093/ofid/ofaa291
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author Doyle, Michelle
Vodstrcil, Lenka A
Plummer, Erica L
Aguirre, Ivette
Fairley, Christopher K
Bradshaw, Catriona S
author_facet Doyle, Michelle
Vodstrcil, Lenka A
Plummer, Erica L
Aguirre, Ivette
Fairley, Christopher K
Bradshaw, Catriona S
author_sort Doyle, Michelle
collection PubMed
description In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%–85%), and minocycline cured 71% (95% CI, 54%–85%) of cases. These data provide useful estimates to inform clinical practice.
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spelling pubmed-74081852020-08-10 Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance Doyle, Michelle Vodstrcil, Lenka A Plummer, Erica L Aguirre, Ivette Fairley, Christopher K Bradshaw, Catriona S Open Forum Infect Dis Brief Reports In the era of increasing macrolide- and quinolone-resistant Mycoplasma genitalium (MG), we report the efficacy of 2 nonquinolone antimicrobials in patients with limited treatment options. Pristinamycin + doxycycline cured 75% (95% CI, 64%–85%), and minocycline cured 71% (95% CI, 54%–85%) of cases. These data provide useful estimates to inform clinical practice. Oxford University Press 2020-07-13 /pmc/articles/PMC7408185/ /pubmed/32782911 http://dx.doi.org/10.1093/ofid/ofaa291 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Doyle, Michelle
Vodstrcil, Lenka A
Plummer, Erica L
Aguirre, Ivette
Fairley, Christopher K
Bradshaw, Catriona S
Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance
title Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance
title_full Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance
title_fullStr Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance
title_full_unstemmed Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance
title_short Nonquinolone Options for the Treatment of Mycoplasma genitalium in the Era of Increased Resistance
title_sort nonquinolone options for the treatment of mycoplasma genitalium in the era of increased resistance
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408185/
https://www.ncbi.nlm.nih.gov/pubmed/32782911
http://dx.doi.org/10.1093/ofid/ofaa291
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