Cargando…

Inflammation in Parkinson’s Disease: Mechanisms and Therapeutic Implications

Parkinson’s disease (PD) is a common neurodegenerative disorder primarily characterized by the death of dopaminergic neurons that project from the substantia nigra pars compacta. Although the molecular bases for PD development are still little defined, extensive evidence from human samples and anima...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pajares, Marta, I. Rojo, Ana, Manda, Gina, Boscá, Lisardo, Cuadrado, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408280/ https://www.ncbi.nlm.nih.gov/pubmed/32674367 http://dx.doi.org/10.3390/cells9071687

Ejemplares similares

Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
por: Pajares, Marta, et al.
Publicado: (2017)

Nordihydroguaiaretic Acid: From Herbal Medicine to Clinical Development for Cancer and Chronic Diseases
por: Manda, Gina, et al.
Publicado: (2020)

Whole Blood Expression Pattern of Inflammation and Redox Genes in Mild Alzheimer’s Disease
por: Milanesi, Elena, et al.
Publicado: (2021)

Can Activation of NRF2 Be a Strategy against COVID-19?
por: Cuadrado, Antonio, et al.
Publicado: (2020)

Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A
por: Pajares, Marta, et al.
Publicado: (2018)

Inflammation and Alzheimer's Disease: Mechanisms and Therapeutic Implications by Natural Products
por: Rather, Mashoque Ahmad, et al.
Publicado: (2021)

Altered Blood and Brain Expression of Inflammation and Redox Genes in Alzheimer’s Disease, Common to APP(V717I) × TAU(P301L) Mice and Patients
por: Cucos, Catalina Anca, et al.
Publicado: (2022)

Ceramide Metabolism and Parkinson’s Disease—Therapeutic Targets
por: Custodia, Antía, et al.
Publicado: (2021)

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development
por: Robledinos-Antón, Natalia, et al.
Publicado: (2019)

Identification of conserved domains in the promoter regions of nitric oxide synthase 2: implications for the species-specific transcription and evolutionary differences
por: Rico, Daniel, et al.
Publicado: (2007)

Toll-like receptors and NLRP3 inflammasome-dependent pathways in Parkinson’s disease: mechanisms and therapeutic implications
por: Soraci, Luca, et al.
Publicado: (2022)

Cyclooxygenase 2 in liver dysfunction and carcinogenesis: Facts and perspectives
por: Martín-Sanz, Paloma, et al.
Publicado: (2017)

Basic mechanisms of rTMS: Implications in Parkinson's disease
por: Arias-Carrión, Oscar
Publicado: (2008)

The Role of Free Radicals in Autophagy Regulation: Implications for Ageing
por: Pajares, M., et al.
Publicado: (2018)

Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
por: El-Sharkawy, Ahmed, et al.
Publicado: (2020)

Repurposing Zileuton as a Depression Drug Using an AI and In Vitro Approach
por: Kubick, Norwin, et al.
Publicado: (2020)

Mechanisms and therapeutic applications of electromagnetic therapy in Parkinson’s disease
por: Vadalà, Maria, et al.
Publicado: (2015)

c-Abl and Parkinson’s Disease: Mechanisms and Therapeutic Potential
por: Brahmachari, Saurav, et al.
Publicado: (2017)

Microglial Phenotypes and Their Relationship to the Cannabinoid System: Therapeutic Implications for Parkinson’s Disease
por: Kelly, Rachel, et al.
Publicado: (2020)

NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health
por: Fernández-García, Victoria, et al.
Publicado: (2021)

The epigenetic mechanisms involved in mitochondrial dysfunction: Implication for Parkinson’s disease
por: Chen, Zixuan, et al.
Publicado: (2021)

Self-defense of macrophages against oxidative injury: Fighting for their own survival
por: Virág, László, et al.
Publicado: (2019)

Immune and Inflammation in Acute Coronary Syndrome: Molecular Mechanisms and Therapeutic Implications
por: Wang, Haiming, et al.
Publicado: (2020)

Obesity, Inflammation, and Postmenopausal Breast Cancer: Therapeutic Implications
por: Macciò, Antonio, et al.
Publicado: (2011)

LRRK2, GBA and their interaction in the regulation of autophagy: implications on therapeutics in Parkinson's disease
por: Pang, Shirley Yin-Yu, et al.
Publicado: (2022)

Mitophagy in Parkinson’s Disease: Pathogenic and Therapeutic Implications
por: Gao, Fei, et al.
Publicado: (2017)

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications
por: González, Nieves, et al.
Publicado: (2017)

Editorial: Inflammation and cardiovascular disease: Vascular responses, mechanisms and therapeutic implications
por: Villalba, Nuria, et al.
Publicado: (2022)

Intestinal Inflammation and Parkinson’s Disease
por: Li, Yu, et al.
Publicado: (2021)

Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy
por: Rojo, Ana I., et al.
Publicado: (2018)

The Interaction between Obstructive Sleep Apnea and Parkinson's Disease: Possible Mechanisms and Implications for Cognitive Function
por: Kaminska, Marta, et al.
Publicado: (2015)

Post-translational modifications of prostaglandin-endoperoxide synthase 2 in colorectal cancer: An update
por: Jaén, Rafael I, et al.
Publicado: (2018)

The Role of Pathogens and Anti-Infective Agents in Parkinson’s Disease, from Etiology to Therapeutic Implications
por: Shen, Si, et al.
Publicado: (2022)

Signaling pathways in Parkinson’s disease: molecular mechanisms and therapeutic interventions
por: Dong-Chen, Xu, et al.
Publicado: (2023)

Autophagy in Heart Failure: Insights into Mechanisms and Therapeutic Implications
por: Bielawska, Magdalena, et al.
Publicado: (2023)

Parkinson's Disease and Systemic Inflammation
por: Ferrari, Carina C., et al.
Publicado: (2011)

Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance
por: Burns, Jorge S., et al.
Publicado: (2017)

Inflammation and cardiovascular disease: From mechanisms to therapeutics
por: Alfaddagh, Abdulhamied, et al.
Publicado: (2020)

Mechanisms Involved in Epileptogenesis in Alzheimer’s Disease and Their Therapeutic Implications
por: Altuna, Miren, et al.
Publicado: (2022)

Resolution-Based Therapies: The Potential of Lipoxins to Treat Human Diseases
por: Jaén, Rafael I., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bdikjghqpcoi6svt00gsece3on